Corticotropin

Introduction

Corticotropin is a medication derived from the adrenocorticotropic hormone (ACTH). It is primarily used to diagnose and treat various conditions related to hormone imbalance and inflammation. Corticotropin stimulates the adrenal glands to release cortisol, a hormone that helps manage inflammation, immune responses, and other body functions. It is available in injection form and is often prescribed when corticosteroid therapy is required but oral administration is not suitable. This medicine is commonly used in both adults and children under medical supervision.

Uses of Corticotropin

• Rheumatoid arthritis
• Systemic lupus erythematosus (SLE)
• Multiple sclerosis (MS) flare-ups
• Psoriatic arthritis and dermatomyositis
• Adrenal gland function testing
• Infantile spasms (West syndrome)

How Corticotropin works

Corticotropin works by stimulating the adrenal cortex to release cortisol and other glucocorticoids. These hormones help reduce inflammation, suppress immune system activity, and maintain various metabolic functions. It acts as a diagnostic and therapeutic agent in managing hormonal deficiencies and inflammatory conditions.

Benefits of Corticotropin

• Effective in managing severe inflammatory and autoimmune conditions
• Useful alternative when corticosteroids cannot be taken orally
• Helpful in diagnosing adrenal gland disorders
• Treats rare neurological conditions like infantile spasms

How to take Corticotropin

Corticotropin is usually administered by injection into a muscle or under the skin, depending on the condition being treated. It should be given by a healthcare professional. Follow the prescribed dosage schedule strictly, and do not skip or double the dose. Regular monitoring may be needed to assess hormone levels and treatment response.

Type of Dosage Available

• Injection (Intramuscular or Subcutaneous)
• Gel form for prolonged action

Side effects of Corticotropin

• Weight gain
• Fluid retention or swelling
• High blood pressure
• Increased blood sugar levels
• Mood swings, irritability, or insomnia
• Weakened immune response
• Muscle weakness and bone thinning (with long-term use)

Safety Advice

• Inform your doctor if you have diabetes, infections, or heart problems
• Do not stop medication abruptly without consulting your doctor
• Use with caution during pregnancy and breastfeeding
• Regular blood tests may be required to monitor side effects
• Avoid contact with people who have infections during treatment

Frequently Asked Questions (FAQs)

Q: What is Corticotropin used for?
A: Corticotropin is used to treat autoimmune conditions, manage inflammation, and diagnose adrenal gland function.

Q: How is Corticotropin administered?
A: It is usually given as an injection either into the muscle or under the skin by a healthcare provider.

Q: Is Corticotropin safe during pregnancy?
A: Use during pregnancy should be done under medical supervision, as the effects can vary based on the condition being treated.

Q: Can Corticotropin cause weight gain?
A: Yes, weight gain is a common side effect due to fluid retention and hormonal changes.

Q: Does Corticotropin affect immunity?
A: Yes, it can suppress the immune system, increasing the risk of infections.