Isoniazid

Isoniazid is a widely used antibiotic primarily prescribed for the prevention and treatment of tuberculosis (TB). It belongs to the class of anti-tuberculars and works by inhibiting the growth of bacteria named "Mycobacterium tuberculosis." Isoniazid is often used alone for latent TB infection or in combination with other anti-TB drugs for active TB. Its early use can prevent disease progression and reduce the risk of complications. Regular monitoring of liver function is essential during treatment due to potential hepatotoxicity. Always complete the full course to maintain treatment efficacy and to avoid resistance.

Uses of Isoniazid

• Treats Tuberculosis: Kills the TB bacteria by disrupting the synthesis of their cell wall. It is a cornerstone drug, used in combination with other medicines to ensure complete eradication of the infection, minimize relapse, and prevent drug resistance.
• Prevents TB Infection: Prevents latent TB from becoming active disease. It is administered to high-risk individuals, like those recently exposed or with weakened immunity, to protect their lungs and other organs from severe TB damage.
• Supports Combination Therapy: Kills bacteria and boosts other TB drugs’ effectiveness. It is key in multi-drug TB treatment, allowing shorter therapy, complete bacterial clearance, and higher success rates, making it essential for effective and efficient TB care.

How Isoniazid Works

Isoniazid works by inhibiting the synthesis of mycolic acid, an essential component of the tuberculosis bacteria`s cell wall. Without this, the bacteria cannot survive, stopping its growth and preventing the infection from spreading in the body.

Benefits of Isoniazid

• Highly effective against tuberculosis bacteria
• Prevents latent TB from becoming active
• Well-tolerated when taken as prescribed
• Can be used in both adults and children

How to Take Isoniazid

Isoniazid should be taken exactly as prescribed by a doctor. It is usually taken once daily on an empty stomach, either one hour before or two hours after meals. If stomach upset occurs, it may be taken with food. The duration of treatment can vary from several months to a year, depending on the condition.

Types of Dosage Available

• 100 mg tablets
• 300 mg tablets
• Oral suspension (liquid form)

Side Effects of Isoniazid

• Nausea and vomiting
• Liver toxicity (hepatitis)
• Numbness and tingling in hands and feet (neuropathy)
• Loss of appetite
• Skin rashes and allergic reactions
• Mood changes or dizziness

Safety Advice

• Avoid alcohol consumption to prevent liver damage
• Take vitamin B6 (pyridoxine) to prevent nerve-related side effects
• Inform the doctor about any existing liver disease
• Complete the full course of treatment as prescribed
• Not recommended for patients with severe liver conditions

Frequently Asked Questions (FAQs)

Q: What is Isoniazid used for?
A: Isoniazid is used for treating and preventing tuberculosis (TB).

Q: How long should I take Isoniazid?
A: Treatment duration varies but usually lasts from 6 to 12 months.

Q: Can I take Isoniazid with food?
A: It is best taken on an empty stomach, but if stomach upset occurs, it can be taken with food.

Q: What precautions should I take while using Isoniazid?
A: Avoid alcohol and take vitamin B6 to reduce nerve-related side effects.

Q: Where can I buy Isoniazid?
A: You can buy Isoniazid from Zeelab Pharmacy at the best price.