Abemaciclib

Abemaciclib is an oral medication used to treat certain types of breast cancer, particularly hormone receptor-positive (HR+), HER2-negative advanced or metastatic breast cancer. It works by inhibiting specific proteins called cyclin-dependent kinases (CDK4 and CDK6) that help cancer cells grow and divide. This targeted therapy slows down cancer progression and is often used alongside hormone therapy.

Uses of Abemaciclib

• Treatment of HR+, HER2-negative advanced or metastatic breast cancer
• Used in combination with hormone therapy
• Helps to slow cancer cell growth

How Abemaciclib Works

Abemaciclib blocks the action of CDK4 and CDK6 enzymes, which are essential for cancer cell division, thereby slowing tumor growth and spread.

Benefits of Abemaciclib

• Targets specific cancer cell pathways
• Improves progression-free survival in breast cancer patients
• Can be taken orally for convenience

How to Take Abemaciclib

Take Abemaciclib tablets orally twice daily with or without food, as prescribed by your doctor. Follow dosing instructions carefully and do not skip doses.

Type of Dosage Available

• Oral tablets

Side Effects of Abemaciclib

• Diarrhea
• Nausea and vomiting
• Fatigue
• Low blood cell counts
• Infections

Safety Advice

• Inform your doctor about any infections or low blood counts
• Avoid grapefruit and grapefruit juice
• Do not stop treatment without consulting your doctor
• Report severe side effects immediately

Frequently Asked Questions (FAQs)

Q. What type of cancer is Abemaciclib used for?
A. It is used to treat hormone receptor-positive, HER2-negative advanced breast cancer.


Q. How should I take Abemaciclib?
A. Take it orally twice daily as prescribed by your doctor.


Q. Can Abemaciclib cause diarrhea?
A. Yes, diarrhea is a common side effect and should be managed with your doctor's advice.


Q. Are there any dietary restrictions?
A. Avoid grapefruit and grapefruit juice while taking Abemaciclib.


Q. Should I inform my doctor about infections?
A. Yes, inform your doctor immediately if you develop signs of infection.