Adrenocorticotropic Hormone (ACTH)

Introduction

Adrenocorticotropic hormone (ACTH) is a naturally occurring hormone that plays a vital role in regulating cortisol production in the adrenal glands. ACTH medications are used for diagnostic and therapeutic purposes, especially in conditions involving adrenal insufficiency or inflammation. It helps stimulate the adrenal glands to release cortisol, a key hormone in managing stress, inflammation, and immune response. ACTH therapy is particularly useful in treating certain autoimmune diseases, multiple sclerosis relapses, and some rare pediatric conditions like infantile spasms.

Uses of Adrenocorticotropic Hormone (ACTH)

• Treatment of adrenal insufficiency (Addison’s disease)
• Management of infantile spasms in children
• Diagnosis of adrenal gland function (ACTH stimulation test)
• Relief in autoimmune and inflammatory conditions like lupus and multiple sclerosis
• Used as an anti-inflammatory and immunosuppressive agent

How Adrenocorticotropic Hormone (ACTH) Works

ACTH stimulates the adrenal cortex to release cortisol and other corticosteroids. These hormones help regulate metabolism, immune function, and the body’s response to stress. By increasing cortisol levels, ACTH reduces inflammation and supports adrenal function in patients with hormonal imbalances or autoimmune disorders.

Benefits of Adrenocorticotropic Hormone (ACTH)

• Supports cortisol production in adrenal insufficiency
• Reduces inflammation and immune response
• Useful in diagnosing adrenal gland health
• Helps manage neurological disorders like infantile spasms
• Effective in treating flare-ups of autoimmune conditions

How to Take Adrenocorticotropic Hormone (ACTH)

ACTH is typically administered via intramuscular or subcutaneous injection by a healthcare professional. The dosage and frequency depend on the condition being treated, patient age, and response to therapy. Never self-administer unless instructed by your doctor. Complete the full course of therapy even if symptoms improve early.

Type of Dosage Available

• Injection (intramuscular)
• Injection (subcutaneous)

Side Effects of Adrenocorticotropic Hormone (ACTH)

• Increased blood pressure
• Swelling or fluid retention
• Mood changes or irritability
• Increased risk of infections
• Muscle weakness or fatigue

Safety Advice

• Use only under strict medical supervision
• Inform your doctor if you have diabetes, hypertension, or infections
• Do not stop suddenly; tapering may be required
• Monitor blood pressure and glucose levels during treatment
• Not recommended for long-term use unless prescribed

Frequently Asked Questions (FAQs)

Q: What is Adrenocorticotropic hormone (ACTH) used for?

A: ACTH is used for treating adrenal insufficiency, infantile spasms, autoimmune diseases, and diagnosing adrenal gland function.

Q: How is ACTH administered?

A: It is given by intramuscular or subcutaneous injection, usually by a healthcare provider.

Q: Can ACTH cause side effects?

A: Yes, possible side effects include high blood pressure, mood swings, swelling, and increased infection risk.

Q: Is ACTH safe for children?

A: ACTH is used in children under medical supervision, especially in conditions like infantile spasms.

Q: Can ACTH be used long-term?

A: Long-term use is usually avoided unless necessary, and must be closely monitored by a doctor.