Afatinib Dimaleate

Afatinib Dimaleate is a targeted cancer medicine used to treat certain types of non-small cell lung cancer (NSCLC). It belongs to a class of drugs known as tyrosine kinase inhibitors (TKIs) that work by blocking the action of specific proteins involved in cancer cell growth. Afatinib is particularly effective in patients whose tumors have epidermal growth factor receptor (EGFR) mutations. It is an oral medication and provides an alternative to traditional chemotherapy by focusing directly on cancer-driving mechanisms.

Uses of Afatinib Dimaleate

• Non-small cell lung cancer (NSCLC) with EGFR mutations
• Metastatic lung cancer management
• Maintenance therapy in advanced lung cancer

How Afatinib Dimaleate works

Afatinib Dimaleate works by irreversibly blocking the EGFR and other related receptors that signal cancer cell growth. By targeting these receptors, it slows down or stops the progression of cancer, particularly in tumors with EGFR mutations.

Benefits of Afatinib Dimaleate

• Targets cancer cells with EGFR mutations directly
• Improves progression-free survival in NSCLC patients
• Reduces reliance on conventional chemotherapy
• Oral administration allows convenient at-home treatment
• Delays disease progression in metastatic cancer

How to take Afatinib Dimaleate

Take Afatinib Dimaleate exactly as prescribed by your oncologist. It is usually taken once daily, on an empty stomach (at least 1 hour before or 2 hours after meals). Swallow the tablet whole with water. Do not crush or chew the tablet. Consistency in timing helps maintain steady drug levels in the body.

Type of Dosage Available

• Tablets (20 mg, 30 mg, 40 mg)

Side effects of Afatinib Dimaleate

• Diarrhea
• Skin rash or acne
• Mouth sores
• Loss of appetite
• Nausea and vomiting
• Dry skin
• Liver enzyme changes (in rare cases)

Safety advice

• Inform your doctor about any liver, kidney, or heart conditions
• Use effective contraception during treatment
• Avoid sun exposure; use sunscreen to prevent skin reactions
• Stay hydrated to manage side effects like diarrhea
• Regular blood tests may be required to monitor liver function
• Do not take with food; maintain an empty stomach dosing

Frequently Asked Questions (FAQs)

Q: What is Afatinib Dimaleate used for?
A: It is used to treat non-small cell lung cancer (NSCLC) with EGFR gene mutations.

Q: How should I take Afatinib Dimaleate?
A: Take it on an empty stomach once daily, at the same time each day, as prescribed by your doctor.

Q: Can Afatinib Dimaleate cure lung cancer?
A: It is not a cure but helps control and slow down the progression of cancer, improving survival and quality of life.

Q: What should I do if I miss a dose?
A: Skip the missed dose if it’s close to your next dose. Do not double up. Follow your doctor’s instructions.

Q: Is Afatinib Dimaleate safe during pregnancy?
A: It is not recommended during pregnancy. Women should use contraception and consult their doctor before use.