Apomorphine

Apomorphine is a prescription medication primarily used for the treatment of advanced Parkinson’s disease and erectile dysfunction. It works as a dopamine receptor agonist and helps restore dopamine activity in the brain, which is essential for muscle movement control. In Parkinson’s, it is particularly useful in managing sudden 'off' episodes when other medications stop working. It is fast-acting and is usually given as an injection or sublingual tablet under the supervision of a healthcare provider.

Uses of Apomorphine

• Treatment of Parkinson's disease 'off' episodes
• Improves motor function in Parkinson’s patients
• Used in erectile dysfunction in certain cases
• Helps reduce tremors and muscle stiffness

How Apomorphine works

Apomorphine stimulates dopamine receptors in the brain, mimicking the action of natural dopamine. This helps improve movement, reduce muscle stiffness, and manage sudden motor fluctuations in Parkinson’s disease. It acts quickly, often within minutes of administration.

Benefits of Apomorphine

• Provides rapid relief from 'off' episodes in Parkinson’s
• Improves muscle control and reduces tremors
• Can enhance quality of life in advanced Parkinson’s
• Useful in patients not responding to oral therapy

How to take Apomorphine

Apomorphine is usually administered by subcutaneous injection or sublingual film. The dose and frequency depend on the patient's condition and response. It should be taken only under the supervision of a healthcare provider, and an antiemetic may be prescribed to prevent nausea.

Type of Dosage Available

• Injection
• Sublingual film/tablet

Side effects of Apomorphine

• Nausea and vomiting
• Drowsiness or dizziness
• Low blood pressure (hypotension)
• Hallucinations or confusion
• Injection site reactions
• Yawning or sleep attacks

Safety advice

• Should be used under medical supervision only
• Not recommended for patients with severe liver disease
• Avoid driving or operating machinery after taking
• May interact with alcohol and other medications
• Monitor blood pressure regularly

Frequently Asked Questions (FAQs)

Q: What is Apomorphine used for?
A: Apomorphine is mainly used to treat sudden 'off' episodes in patients with Parkinson’s disease. It may also be used for erectile dysfunction in select cases.

Q: How quickly does Apomorphine work?
A: Apomorphine works within 10 to 20 minutes after administration, providing rapid relief from symptoms.

Q: Can Apomorphine be taken orally?
A: Apomorphine is not available in a traditional oral form. It is given as an injection or sublingual film/tablet that dissolves under the tongue.

Q: Does Apomorphine cause drowsiness?
A: Yes, it may cause drowsiness or sudden sleep attacks. Avoid driving or using machines after taking it.

Q: Is Apomorphine safe in elderly patients?
A: Yes, but it should be used with caution and under medical supervision, especially if the patient has other health conditions.