Apremilast

Apremilast is a prescription medication used to treat psoriasis and psoriatic arthritis. It belongs to a class of drugs called phosphodiesterase 4 (PDE4) inhibitors, which help in reducing inflammation. Apremilast is known for improving symptoms like skin scaling, redness, and joint pain in individuals with psoriasis-related conditions. It offers a convenient oral treatment option for people who do not respond well to other therapies.

Uses of Apremilast

• Treats moderate to severe plaque psoriasis
• Manages psoriatic arthritis symptoms
• Reduces skin inflammation and scaling
• Helps in relieving joint pain and stiffness
• Improves overall quality of life for psoriasis patients

How Apremilast Works

Apremilast works by inhibiting the enzyme phosphodiesterase 4 (PDE4), which plays a role in inflammation. By blocking this enzyme, Apremilast helps in reducing the production of inflammatory substances, leading to decreased swelling, pain, and skin symptoms in psoriasis and psoriatic arthritis patients.

Benefits of Apremilast

• Provides relief from skin inflammation and scaling
• Reduces joint pain and swelling in psoriatic arthritis
• Non-steroidal and does not suppress the immune system
• Convenient oral treatment option
• Improves mobility and daily functioning

How to Take Apremilast

Apremilast is taken orally, usually twice a day with or without food. The dosage is gradually increased over the first few days to reduce the risk of side effects. It is essential to follow the doctor’s prescription for the best results.

Type of Dosage Available

• Apremilast 10 mg Tablets
• Apremilast 20 mg Tablets
• Apremilast 30 mg Tablets

Side Effects of Apremilast

• Nausea and vomiting
• Diarrhea or stomach upset
• Headache or dizziness
• Weight loss
• Fatigue and sleep disturbances
• Depression or mood changes

Safety Advice

• Inform your doctor if you have a history of depression or suicidal thoughts
• Monitor weight regularly during treatment
• Do not take Apremilast if you have severe kidney disease
• Avoid alcohol as it may increase side effects
• Consult a doctor before use if pregnant or breastfeeding

Frequently Asked Questions

Q. What is Apremilast used for?
A. Apremilast is used to treat moderate to severe plaque psoriasis and psoriatic arthritis by reducing inflammation.

Q. How long does it take for Apremilast to work?
A. It may take several weeks to show noticeable improvement in symptoms, with full effects visible after a few months.

Q. Can Apremilast be taken with other medications?
A. Consult your doctor before taking Apremilast with other medications, especially immunosuppressants and strong enzyme inducers.

Q. Does Apremilast cause weight loss?
A. Yes, weight loss is a possible side effect, so regular weight monitoring is advised during treatment.

Q. Can I stop taking Apremilast suddenly?
A. No, stopping Apremilast suddenly may cause symptoms to return. Always consult your doctor before discontinuation.