Asparaginase
Uses of Asparaginase
- Acute lymphoblastic leukemia (ALL)
- Lymphoma (investigational/off-label use)
- Used in multi-drug chemotherapy protocols
- Primarily for pediatric leukemia patients
How Asparaginase works
Asparaginase breaks down asparagine in the blood. Leukemia cells cannot produce this amino acid themselves and depend on external sources. Asparaginase deprives them of asparagine, causing them to die, while normal cells remain less affected.
Benefits of Asparaginase
- Effective in pediatric and adult acute lymphoblastic leukemia
- Targets leukemia cells specifically with minimal effect on normal cells
- Improves long-term survival rates when used in combination therapy
- Available in PEGylated forms for fewer allergic reactions
How to take Asparaginase
Asparaginase is administered by intramuscular or intravenous injection by a healthcare professional. The dosage and schedule depend on the patient`s weight, treatment protocol, and response. Close monitoring is required due to risk of allergic reactions and side effects.
Type of Dosage Available
- Intravenous Injection
- Intramuscular Injection
- PEG-Asparaginase (long-acting form)
Side effects of Asparaginase
- Allergic reactions (rash, breathing difficulty)
- Pancreatitis
- Bleeding or clotting disorders
- Liver enzyme abnormalities
- Fatigue
- Fever
- Abdominal pain
Safety Advice
- Only use under supervision of a cancer specialist
- Regularly monitor liver function and pancreas enzymes
- Be alert for signs of allergic reaction
- Not recommended during pregnancy unless life-saving
- Inform doctor about all current medications and health issues
Frequently Asked Questions (FAQs)
Q: What is Asparaginase used for?
A: It is used to treat acute lymphoblastic leukemia (ALL), mainly in children.
Q: How is Asparaginase given?
A: It is administered through intramuscular or intravenous injection by a healthcare provider.
Q: Is Asparaginase safe?
A: It is safe under medical supervision but may cause serious side effects like allergic reactions and pancreatitis.
Q: Can Asparaginase be used in adults?
A: Yes, it can be used in adults as part of combination chemotherapy for ALL.
Q: What is PEG-Asparaginase?
A: PEG-Asparaginase is a modified long-acting form with fewer allergic reactions and less frequent dosing.
Medicine Not Available for Asparaginase
Uses of Asparaginase
- Acute lymphoblastic leukemia (ALL)
- Lymphoma (investigational/off-label use)
- Used in multi-drug chemotherapy protocols
- Primarily for pediatric leukemia patients
How Asparaginase works
Asparaginase breaks down asparagine in the blood. Leukemia cells cannot produce this amino acid themselves and depend on external sources. Asparaginase deprives them of asparagine, causing them to die, while normal cells remain less affected.
Benefits of Asparaginase
- Effective in pediatric and adult acute lymphoblastic leukemia
- Targets leukemia cells specifically with minimal effect on normal cells
- Improves long-term survival rates when used in combination therapy
- Available in PEGylated forms for fewer allergic reactions
How to take Asparaginase
Asparaginase is administered by intramuscular or intravenous injection by a healthcare professional. The dosage and schedule depend on the patient`s weight, treatment protocol, and response. Close monitoring is required due to risk of allergic reactions and side effects.
Type of Dosage Available
- Intravenous Injection
- Intramuscular Injection
- PEG-Asparaginase (long-acting form)
Side effects of Asparaginase
- Allergic reactions (rash, breathing difficulty)
- Pancreatitis
- Bleeding or clotting disorders
- Liver enzyme abnormalities
- Fatigue
- Fever
- Abdominal pain
Safety Advice
- Only use under supervision of a cancer specialist
- Regularly monitor liver function and pancreas enzymes
- Be alert for signs of allergic reaction
- Not recommended during pregnancy unless life-saving
- Inform doctor about all current medications and health issues
Frequently Asked Questions (FAQs)
Q: What is Asparaginase used for?
A: It is used to treat acute lymphoblastic leukemia (ALL), mainly in children.
Q: How is Asparaginase given?
A: It is administered through intramuscular or intravenous injection by a healthcare provider.
Q: Is Asparaginase safe?
A: It is safe under medical supervision but may cause serious side effects like allergic reactions and pancreatitis.
Q: Can Asparaginase be used in adults?
A: Yes, it can be used in adults as part of combination chemotherapy for ALL.
Q: What is PEG-Asparaginase?
A: PEG-Asparaginase is a modified long-acting form with fewer allergic reactions and less frequent dosing.
Download India's most affordable pharmacy app
- Compare with medicine prices
- Save upto 90% on your medicine bills
Temperature Controlled storage and delivery
Regular Sanitization
Disinfected Packaging
Temperature Checks
No Contact Delivery
Added!