Azathioprine

Azathioprine is an immunosuppressant medication commonly used to prevent organ rejection in transplant patients and treat autoimmune diseases. It works by weakening the immune system, reducing inflammation, and preventing the body from attacking its own tissues. Doctors prescribe Azathioprine for conditions such as rheumatoid arthritis, Crohn’s disease, and lupus. It is available in tablet and injection forms and should be used under strict medical supervision due to potential side effects.

Uses of Azathioprine

• Prevents organ rejection after kidney, liver, or heart transplant
• Treats autoimmune diseases like rheumatoid arthritis and lupus
• Helps manage Crohn’s disease and ulcerative colitis
• Used in dermatological conditions like pemphigus and psoriasis
• Prescribed for multiple sclerosis and other immune-related disorders

How Azathioprine Works

Azathioprine works by interfering with DNA synthesis in immune cells, reducing their ability to attack the body’s tissues. By suppressing the immune response, it helps prevent organ rejection in transplant patients and reduces inflammation in autoimmune diseases.

Benefits of Azathioprine

• Effectively prevents organ rejection in transplant patients
• Reduces inflammation in autoimmune diseases
• Helps manage chronic conditions like rheumatoid arthritis
• Controls symptoms of Crohn’s disease and ulcerative colitis
• Can be used long-term under medical supervision

How to Take Azathioprine

• Take Azathioprine exactly as prescribed by your doctor.
• Swallow the tablet whole with water, preferably after meals.
• Do not crush or chew the tablet.
• If taking an injection, it should be administered by a healthcare professional.
• Regular blood tests may be required to monitor your response.

Type of Dosage Available

• Oral tablets (50 mg, 100 mg)
• Injectable solution

Side Effects of Azathioprine

• Nausea and vomiting
• Increased risk of infections
• Loss of appetite
• Fatigue and weakness
• Low blood cell count
• Liver toxicity (in rare cases)

Safety Advice

• Do not take Azathioprine without medical supervision.
• Inform your doctor about any existing liver or kidney conditions.
• Avoid close contact with people who have infections.
• Use contraception as Azathioprine may harm an unborn baby.
• Do not receive live vaccines while on this medication.

Frequently Asked Questions

Q: What is Azathioprine used for?
A: It is used to prevent organ rejection after transplants and treat autoimmune diseases.

Q: How long does Azathioprine take to work?
A: It may take several weeks to months to show noticeable effects.

Q: Can I stop taking Azathioprine suddenly?
A: No, stopping it suddenly can worsen your condition. Consult your doctor before stopping.

Q: Does Azathioprine cause weight gain?
A: Weight gain is not a common side effect, but changes in appetite may occur.

Q: Is Azathioprine safe for long-term use?
A: Yes, but regular monitoring is required to prevent potential side effects.