Capmatinib

Introduction

Capmatinib is a prescription medicine used primarily for treating non-small cell lung cancer (NSCLC) that carries specific genetic mutations (MET exon 14 skipping). It belongs to a class of targeted cancer therapies called kinase inhibitors, which work by interfering with the growth of cancer cells. This medicine is generally prescribed when cancer has spread to other parts of the body or cannot be removed surgically. Capmatinib is available in tablet form and should only be taken under medical supervision.

Uses of Capmatinib

• Treatment of metastatic non-small cell lung cancer (NSCLC) with MET exon 14 skipping mutations

How Capmatinib works

Capmatinib works by targeting and blocking the activity of a protein called MET, which is involved in cell growth and division. In certain cancers, the MET gene is abnormally active, causing cancer cells to grow uncontrollably. By inhibiting MET, Capmatinib slows or stops the growth of these cancer cells and may help shrink tumors.

Benefits of Capmatinib

• Specifically targets cancer-causing MET gene mutations
• Improves survival rate in advanced NSCLC patients
• Can be taken orally, making it convenient for patients
• Helps reduce tumor size and disease progression

How to take Capmatinib

Capmatinib should be taken exactly as prescribed by your doctor. It is usually taken twice a day with or without food. Do not crush, chew, or split the tablets. Follow your healthcare provider’s instructions and complete the full course of treatment unless advised otherwise. Missed doses should be taken as soon as remembered unless it's near the time of the next dose.

Type of Dosage Available

• Capmatinib 150 mg Tablets
• Capmatinib 200 mg Tablets

Side effects of Capmatinib

• Nausea
• Vomiting
• Swelling in hands or feet
• Tiredness or fatigue
• Loss of appetite
• Increased liver enzymes
• Shortness of breath
• Serious lung or liver issues (rare but severe)

Safety advice

• Not recommended during pregnancy or breastfeeding
• Inform your doctor of liver or kidney problems
• Avoid alcohol and grapefruit juice while taking this medicine
• Use effective contraception during treatment and for a period after
• Regular blood tests may be required to monitor liver function

Frequently Asked Questions (FAQs)

Q1. What is Capmatinib used for?

Capmatinib is used for treating metastatic non-small cell lung cancer (NSCLC) with MET exon 14 skipping mutations.

Q2. How should I take Capmatinib?

Take Capmatinib as prescribed by your doctor, usually twice a day, with or without food. Do not crush or break the tablets.

Q3. Are there any foods or drinks I should avoid?

Yes, avoid grapefruit and grapefruit juice, as they can interfere with how the medicine works.

Q4. Can I take Capmatinib during pregnancy?

No, it is not safe during pregnancy. Use effective contraception during treatment and consult your doctor if planning pregnancy.

Q5. What should I do if I miss a dose?

Take the missed dose as soon as you remember. If it's close to the next dose, skip it. Do not double dose.