Carbetocin

Carbetocin is a synthetic oxytocin analogue used primarily to prevent postpartum hemorrhage (PPH) in women after cesarean section or vaginal delivery. It mimics the natural hormone oxytocin by stimulating uterine contractions, which help reduce bleeding following childbirth. Due to its longer half-life, it offers prolonged effects compared to oxytocin, making it a reliable option for managing postpartum blood loss effectively.

Uses of Carbetocin

• Prevention of postpartum hemorrhage (PPH)
• Promotes uterine contraction after delivery
• Used during cesarean section or normal delivery

How Carbetocin works

Carbetocin binds to oxytocin receptors in the uterine muscle, inducing strong and sustained uterine contractions to reduce bleeding after childbirth.

Benefits of Carbetocin

• Effective in preventing postpartum bleeding
• Longer duration of action than oxytocin
• Reduces need for additional uterotonic drugs

How to take Carbetocin

Carbetocin is administered as a single intravenous (IV) or intramuscular (IM) injection immediately after delivery, as directed by a healthcare professional.

Type of Dosage Available

• Injection (IV/IM)

Side effects of Carbetocin

• Nausea
• Vomiting
• Abdominal pain
• Headache
• Flushing
• Hypotension (low blood pressure)

Safety advice

• Should be administered by a trained healthcare provider
• Not recommended during pregnancy before delivery
• Monitor blood pressure during administration
• Inform your doctor about any allergies or medical conditions

Frequently Asked Questions (FAQs)

Q. What is Carbetocin used for?
A. Carbetocin is used to prevent excessive bleeding (postpartum hemorrhage) after childbirth.

Q. How is Carbetocin administered?
A. It is given as a single injection into a vein or muscle immediately after delivery.

Q. Is Carbetocin safe during pregnancy?
A. No, Carbetocin is not used during pregnancy before delivery. It is only administered after childbirth.

Q. Can Carbetocin cause any side effects?
A. Yes, it may cause nausea, vomiting, flushing, headache, or low blood pressure.

Q. How does Carbetocin differ from oxytocin?
A. Carbetocin has a longer duration of action, reducing the need for repeat dosing compared to oxytocin.