Ceritinib

Ceritinib is a targeted therapy medication used in the treatment of non-small cell lung cancer (NSCLC) that is positive for anaplastic lymphoma kinase (ALK). It belongs to a class of drugs known as ALK inhibitors. Ceritinib works by blocking the activity of ALK proteins that help cancer cells grow and spread. This medicine is often prescribed when the cancer has spread or when previous treatments have not been effective. Ceritinib helps in slowing down or stopping the progression of cancer by specifically attacking cancerous cells with ALK mutations.

Uses of Ceritinib

  • Treatment of ALK-positive non-small cell lung cancer
  • Used in patients who have not responded to other cancer treatments
  • Helps in slowing the growth and spread of lung cancer cells
  • Used in metastatic or advanced-stage lung cancer

How Ceritinib Works

Ceritinib blocks the abnormal ALK protein that promotes the growth of cancer cells. By inhibiting ALK, the medicine stops the multiplication of cancer cells and helps reduce tumor size in ALK-positive non-small cell lung cancer.

Benefits of Ceritinib

  • Targets cancer cells with high precision
  • Effective in ALK-positive NSCLC
  • Improves survival rates in advanced cancer cases
  • Reduces tumor progression
  • Can be taken orally at home

How to Take Ceritinib

Ceritinib should be taken exactly as prescribed by your doctor. Usually, it is taken once a day with food. Swallow the tablet whole with water; do not crush or chew it. Continue taking the medicine even if you feel well, unless your doctor advises otherwise. Regular monitoring is required during the course of treatment.

Type of Dosage Available

  • Tablet
  • Capsule (in some brands)

Side Effects of Ceritinib

  • Nausea and vomiting
  • Diarrhea
  • Fatigue
  • Elevated liver enzymes
  • Abdominal pain
  • Decreased appetite
  • High blood sugar (hyperglycemia)

Safety Advice

  • Inform your doctor about any liver, heart, or kidney issues
  • Avoid alcohol during treatment
  • Do not take if pregnant or breastfeeding without doctor’s advice
  • Routine liver function tests may be required
  • May interact with other medications – consult your doctor

Frequently Asked Questions (FAQs)

Q. What is Ceritinib used for?
A. Ceritinib is used to treat ALK-positive non-small cell lung cancer, especially in advanced stages.

Q. How long can I take Ceritinib?
A. You should take it as long as your doctor recommends. Treatment duration depends on your response and side effects.

Q. Can Ceritinib be taken with food?
A. Yes, Ceritinib should be taken with food to improve absorption and reduce stomach upset.

Q. Is Ceritinib chemotherapy?
A. No, Ceritinib is not traditional chemotherapy. It is a targeted therapy that specifically inhibits the ALK protein in cancer cells.

Q. What precautions should I follow while on Ceritinib?
A. Avoid alcohol, follow up with regular blood tests, and inform your doctor about any side effects or other medications you’re taking.

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