Cetuximab

Cetuximab is a monoclonal antibody used to treat certain types of cancers, including colorectal cancer and head and neck cancer. It works by targeting the epidermal growth factor receptor (EGFR), which is often overexpressed in some cancers. By blocking EGFR, Cetuximab helps slow or stop the growth of cancer cells. It is usually administered as an intravenous infusion under medical supervision in a hospital or clinic setting.

Uses of Cetuximab

  • Metastatic colorectal cancer
  • Head and neck cancer
  • EGFR-positive cancers

How Cetuximab works

Cetuximab binds to the epidermal growth factor receptor (EGFR) on cancer cells, blocking the signals that promote tumor growth and survival, thereby slowing or stopping cancer progression.

Benefits of Cetuximab

  • Improves survival rates in certain cancers
  • Effective in tumors with EGFR overexpression
  • May be used in combination with chemotherapy or radiation

How to take Cetuximab

Cetuximab is given as an intravenous (IV) infusion by a healthcare professional, typically once a week. The dose and schedule depend on the type and stage of cancer being treated.

Type of Dosage Available

  • Intravenous infusion (Injection)

Side effects of Cetuximab

  • Skin rash
  • Infusion-related reactions
  • Fever
  • Low magnesium levels
  • Fatigue
  • Diarrhea
  • Nausea

Safety advice

  • Administered under medical supervision only
  • Regular monitoring of electrolytes and kidney function is recommended
  • Inform your doctor if you have heart or lung problems
  • Use sunscreen and protective clothing to avoid sun sensitivity
  • Not recommended during pregnancy or breastfeeding unless clearly needed

Frequently Asked Questions (FAQs)


Q. What is Cetuximab used for?
A. Cetuximab is used to treat metastatic colorectal cancer and certain head and neck cancers by targeting EGFR.

Q. How is Cetuximab administered?
A. It is given as an intravenous infusion under the supervision of a healthcare professional.

Q. Can Cetuximab cause skin problems?
A. Yes, skin rash is a common side effect and may require treatment with topical or oral medications.

Q. Is Cetuximab used alone or with other therapies?
A. It may be used alone or in combination with chemotherapy or radiation depending on the cancer type.

Q. Is Cetuximab safe during pregnancy?
A. It is not recommended during pregnancy. Discuss with your doctor if you are pregnant or planning to conceive.

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