Dalfampridine

Dalfampridine is a medication primarily prescribed to improve walking ability in individuals with multiple sclerosis (MS). It works as a potassium channel blocker, helping nerve signals travel more efficiently in damaged nerves, thereby enhancing muscle coordination and walking speed.

Uses

• Improvement of walking in patients with multiple sclerosis (MS)

How it works

Dalfampridine blocks potassium channels on the surface of nerve fibers, allowing more efficient nerve signal transmission in demyelinated nerves (damaged by MS). This enhances communication between the brain and muscles, thereby improving mobility.

Benefits

• Improves walking speed in people with MS
• Enhances muscle coordination
• May help maintain independence and mobility

How to take

Dalfampridine is typically taken orally in the form of extended-release tablets. It should be swallowed whole, with or without food, and taken exactly as prescribed—usually every 12 hours. Do not crush, chew, or split the tablets.

Type of Dosage Available

• Extended-release tablets

Side effects

• Seizures
• Urinary tract infections
• Insomnia
• Dizziness
• Headache
• Nausea
• Back pain
• Balance disorders

Safety advice

• Not recommended for patients with a history of seizures
• Use with caution in patients with kidney problems
• Regular kidney function monitoring may be needed
• Avoid alcohol as it may increase the risk of side effects
• Not recommended during pregnancy or breastfeeding unless advised by a doctor

Frequently Asked Questions (FAQs)

Q. What is Dalfampridine used for?
A. Dalfampridine is used to improve walking in individuals suffering from multiple sclerosis (MS).

Q. How does Dalfampridine help MS patients?
A. It enhances nerve signal conduction in damaged nerves, improving muscle control and walking speed.

Q. Can Dalfampridine cause seizures?
A. Yes, seizures are a known risk, especially in those with a history of seizures or impaired kidney function.

Q. How long does it take for Dalfampridine to work?
A. Some patients may see improvement in walking within a few weeks, but response varies between individuals.

Q. Can I stop taking Dalfampridine suddenly?
A. You should consult your doctor before stopping the medication, even if you feel better, to avoid complications.