Deferiprone

Deferiprone is a medication used to reduce excess iron in the body, a condition known as iron overload. It is especially helpful for patients with conditions like thalassemia, who receive frequent blood transfusions that can lead to iron buildup. Deferiprone belongs to a class of drugs called iron chelators. By binding to iron, it helps remove it from the body through urine. This treatment helps prevent damage to vital organs caused by too much iron.

Uses of Deferiprone

• Treats iron overload in patients receiving regular blood transfusions
• Used in thalassemia major to prevent organ damage due to excess iron
• Sometimes used in other conditions with high iron levels when other treatments are not suitable

How Deferiprone Works

Deferiprone works by binding with excess iron in the bloodstream. This bound iron is then safely removed from the body through urine. This reduces iron buildup and protects organs from iron-related damage.

Benefits of Deferiprone

• Effectively removes excess iron from the body
• Prevents damage to organs like the liver and heart
• Useful when other iron chelators are not effective or tolerated
• Can be taken orally, making it easy to use

How to Take Deferiprone

Deferiprone is usually taken by mouth, three times a day. It can be taken with or without food, but taking it with meals may help reduce stomach upset. The dosage is based on body weight and medical condition. Always follow your doctor’s instructions carefully and do not skip doses.

Type of Dosage Available

• Deferiprone Oral Tablets
• Deferiprone Oral Solution
• Deferiprone Extended Release Tablets

Side Effects of Deferiprone

• Nausea and vomiting
• Stomach pain
• Joint pain
• Low white blood cell count (can increase infection risk)
• Liver enzyme changes
• Red-colored urine (harmless)

Safety Advice

• Regular blood tests are needed to monitor white blood cells and liver function
• Inform your doctor if you have liver or kidney problems
• Do not take with aluminum-containing antacids
• Not recommended during pregnancy or breastfeeding without doctor’s advice
• Store in a cool, dry place away from direct sunlight

Frequently Asked Questions (FAQs)

Q: What is Deferiprone used for?
A: Deferiprone is used to treat iron overload in patients who receive frequent blood transfusions, such as those with thalassemia.

Q: Can I take Deferiprone without food?
A: Yes, but it is usually recommended to take it with food to avoid stomach upset.

Q: Is red-colored urine normal while using Deferiprone?
A: Yes, red or brown urine is a common and harmless effect of iron being removed from your body.

Q: Are there any serious side effects of Deferiprone?
A: In rare cases, it may lower white blood cell counts. Regular blood tests are needed to monitor this.

Q: Can I take other medications with Deferiprone?
A: You should consult your doctor before combining Deferiprone with other medications, especially antacids or supplements containing aluminum.