Desidustat

Desidustat is a medicine used for the treatment of anemia (low red blood cell count) in patients suffering from chronic kidney disease (CKD), whether they are on dialysis or not. It is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) that helps boost the body’s natural production of erythropoietin, a hormone that stimulates red blood cell formation. Desidustat offers a convenient oral option over traditional injections for managing anemia caused by kidney disorders.

Uses of Desidustat

• Treatment of anemia due to chronic kidney disease
• Management of anemia in dialysis and non-dialysis patients
• Improves hemoglobin levels in CKD patients
• Reduces the need for injectable erythropoiesis-stimulating agents (ESAs)

How Desidustat works

Desidustat works by inhibiting the prolyl hydroxylase enzymes that normally break down hypoxia-inducible factors (HIFs). This stabilizes HIF levels, stimulating the body to produce more erythropoietin, which helps in increasing red blood cell production and correcting anemia.

Benefits of Desidustat

• Convenient oral alternative to injections
• Effective in both dialysis and non-dialysis CKD patients
• Improves red blood cell count
• Reduces need for iron supplements and transfusions
• May improve overall quality of life in CKD patients

How to take Desidustat

Take Desidustat exactly as prescribed by your doctor. It is usually taken by mouth once daily, with or without food. Do not skip or double doses. Regular blood tests may be required to monitor hemoglobin levels and kidney function. Follow your doctor’s instructions carefully for the best results.

Type of Dosage Available

• Oral tablets

Side effects of Desidustat

• High blood pressure (hypertension)
• Headache
• Diarrhea
• Nausea
• Dizziness
• Increased risk of blood clots (rare)

Safety advice

• Not recommended for use during pregnancy without medical advice
• Regular monitoring of blood pressure is advised
• Inform your doctor about liver or heart conditions
• Use with caution in patients with a history of blood clots
• Do not stop the medicine without consulting your doctor
• Keep out of reach of children

Frequently Asked Questions (FAQs)

Q. What is Desidustat used for?
A. Desidustat is used to treat anemia in people with chronic kidney disease, both on dialysis and not on dialysis.

Q. How long does it take for Desidustat to show results?
A. It may take a few weeks to improve hemoglobin levels. Regular monitoring is essential for proper dosing.

Q. Can Desidustat be taken with food?
A. Yes, Desidustat can be taken with or without food. Follow your doctor’s instructions for best results.

Q. Are there any serious side effects of Desidustat?
A. Serious side effects like high blood pressure or blood clots are rare but possible. Always consult your doctor if you notice unusual symptoms.

Q. Can Desidustat be used in children?
A. Desidustat is currently not recommended for use in children unless specifically advised by a healthcare provider.