Dimethyl Fumarate

Dimethyl Fumarate is an oral medication primarily used to treat relapsing forms of multiple sclerosis (MS). It belongs to the class of drugs known as immunomodulators. This medicine helps reduce the frequency of MS relapses and slows down the progression of physical disability. Dimethyl Fumarate works by modulating the immune system and reducing inflammation that damages nerves in MS patients.

Uses of Dimethyl Fumarate

• Treatment of relapsing forms of multiple sclerosis (MS)
• Reduction in the number of MS flare-ups
• Slows the progression of physical disability in MS
• Improves quality of life in MS patients

How Dimethyl Fumarate Works

Dimethyl Fumarate activates the Nrf2 pathway, which reduces oxidative stress and inflammation in the nervous system. This helps protect nerve cells from damage caused by multiple sclerosis.

Benefits of Dimethyl Fumarate

• Reduces the number and severity of MS relapses
• Slows the advancement of MS-related disability
• Convenient oral dosing compared to injectable treatments
• Anti-inflammatory and neuroprotective properties

How to Take Dimethyl Fumarate

Dimethyl Fumarate is taken orally, typically twice daily with food to reduce stomach upset. Follow your doctor’s instructions carefully. Do not crush, chew, or split the capsules.

Type of Dosage Available

• Oral capsules

Side Effects of Dimethyl Fumarate

• Flushing (redness, warmth)
• Stomach pain, nausea, or diarrhea
• Itching or rash
• Low white blood cell count
• Liver enzyme elevation

Safety Advice

• Take with food to reduce gastrointestinal side effects
• Regular blood tests may be needed to monitor liver and white blood cell levels
• Inform your doctor if you experience persistent infections
• Not recommended during pregnancy without medical advice
• Store in a cool, dry place away from direct sunlight

Frequently Asked Questions (FAQs)

Q: What is Dimethyl Fumarate used for?
A: It is used to treat relapsing forms of multiple sclerosis and reduce the frequency of flare-ups.

Q: How does Dimethyl Fumarate help in MS?
A: It reduces inflammation and oxidative stress in the nervous system, protecting against nerve damage.

Q: Can I take Dimethyl Fumarate with other MS medications?
A: Only under the supervision of your doctor, as combining medications may require dose adjustments.

Q: What should I do if I miss a dose?
A: Take the missed dose as soon as you remember, unless it's almost time for your next dose. Do not double dose.

Q: Is Dimethyl Fumarate safe for long-term use?
A: Yes, it is commonly prescribed for long-term MS management but requires regular monitoring.