Eltrombopag

Eltrombopag is a medication primarily used to treat low platelet counts in patients with conditions such as chronic immune thrombocytopenia (ITP) and severe aplastic anemia. It works by stimulating the production of platelets in the bone marrow, which helps prevent excessive bleeding due to low platelet levels. Eltrombopag is generally prescribed when other treatments have been ineffective in increasing platelet count. It is taken orally and should be used under the guidance of a healthcare provider.

Uses of Eltrombopag

  • Treats chronic immune thrombocytopenia (ITP), a condition where the immune system destroys platelets.
  • Used in patients with severe aplastic anemia to help increase platelet production.
  • Helps in reducing the risk of bleeding due to low platelet counts.
  • May be used in other blood disorders that result in low platelet levels, as prescribed by a healthcare provider.

How Eltrombopag Works

Eltrombopag works by stimulating the production of platelets from the bone marrow, increasing the number of platelets in the blood. It activates the thrombopoietin receptor, which is essential for the production of platelets. This helps prevent bleeding caused by low platelet counts in patients with conditions like ITP and severe aplastic anemia.

Benefits of Eltrombopag

  • Helps increase platelet counts, reducing the risk of bleeding.
  • Improves overall quality of life for patients with chronic immune thrombocytopenia (ITP).
  • May reduce the need for platelet transfusions in severe cases.
  • Effective in treating low platelet count in patients with severe aplastic anemia.

How to Take Eltrombopag

Eltrombopag is typically taken as an oral tablet once a day. It is important to follow the dosage instructions provided by your healthcare provider. The tablets should be taken on an empty stomach, at least 1 hour before or 2 hours after meals. Do not crush or chew the tablets. It’s important to avoid taking Eltrombopag with certain foods or medications that may interfere with its absorption, such as dairy products or antacids.

Types of Dosage Available

  • Tablets (Available in various strengths, typically 25 mg, 50 mg, 75 mg, and 100 mg).

Side Effects of Eltrombopag

  • Common side effects may include headaches, fatigue, or nausea.
  • Some patients may experience upper respiratory tract infections or sore throat.
  • More serious side effects include liver problems, indicated by yellowing of the skin or eyes.
  • Increased risk of blood clots and abnormal liver enzyme levels may also occur.
  • Consult your doctor if you experience unusual bleeding or bruising, as this may indicate a serious condition.

Safety Advice

  • Consult a healthcare provider before starting treatment, especially if pregnant, breastfeeding, or suffering from liver disease.
  • Regular monitoring of liver function and blood platelet count is necessary during treatment.
  • Do not take with certain medications or foods, as they may interfere with the absorption of Eltrombopag.
  • Store the medication in a cool, dry place away from sunlight and keep out of reach of children.

Frequently Asked Questions (FAQs)

Q: Can I take Eltrombopag with other medications?

A: It is important to consult your doctor before taking Eltrombopag with any other medications, as there may be interactions with certain drugs.

Q: How long should I take Eltrombopag?

A: The duration of treatment depends on the underlying condition and the effectiveness of the medication. Your doctor will provide guidance on how long you should continue taking it.

Q: Can I stop taking Eltrombopag if I feel better?

A: It is important not to stop taking Eltrombopag without consulting your doctor, as it could affect the effectiveness of your treatment.

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