Emtricitabine + Tenofovir Alafenamide

Introduction

Emtricitabine + Tenofovir Alafenamide is a fixed-dose combination of two antiretroviral medications used for the treatment and prevention of HIV-1 infection. It belongs to the class of nucleoside reverse transcriptase inhibitors (NRTIs), which work by blocking the action of reverse transcriptase, an enzyme HIV needs to multiply. This composition is used in both adults and adolescents and is often prescribed as part of a complete antiretroviral therapy (ART) regimen. It is also used in pre-exposure prophylaxis (PrEP) to reduce the risk of acquiring HIV.

Uses of Emtricitabine + Tenofovir Alafenamide

• Treatment of HIV-1 infection in combination with other antiretrovirals
• Pre-exposure prophylaxis (PrEP) to prevent HIV in high-risk individuals
• Improves immune system function by reducing viral load

How Emtricitabine + Tenofovir Alafenamide Works

This combination works by inhibiting the activity of reverse transcriptase, an enzyme required for HIV replication. By blocking this enzyme, the drugs prevent the virus from multiplying and help reduce the amount of HIV in the body, supporting immune function and lowering the risk of transmission.

Benefits of Emtricitabine + Tenofovir Alafenamide

• Once-daily dosing improves adherence
• Effective in lowering HIV viral load
• Reduces risk of HIV transmission
• Used for both treatment and prevention (PrEP)
• Well-tolerated with fewer kidney and bone side effects than older versions

How to Take Emtricitabine + Tenofovir Alafenamide

This medicine should be taken once daily with or without food, as directed by your doctor. It is important to take it at the same time each day. Do not skip doses to maintain consistent protection or treatment efficacy. Always follow the full course prescribed.

Type of Dosage Available

• Oral tablets

Side Effects of Emtricitabine + Tenofovir Alafenamide

• Nausea or diarrhea
• Fatigue or headache
• Weight gain
• Rash or skin reactions
• In rare cases: liver problems or lactic acidosis
• Changes in kidney or bone health (less common with Alafenamide)

Safety Advice

• Use under medical supervision only
• Not a cure for HIV; continue all medications as prescribed
• Regular monitoring of liver and kidney function is recommended
• Inform your doctor about other medicines you are taking
• Not suitable for use in children under a certain weight or age (as advised)

Frequently Asked Questions (FAQs)

Q: Can Emtricitabine + Tenofovir Alafenamide cure HIV?

A: No, it controls HIV but does not cure it. It helps lower viral load and supports the immune system.

Q: How long do I need to take this medicine?

A: For HIV treatment, it is a lifelong therapy. For PrEP, it is taken as long as risk of exposure exists.

Q: Is it safe to take during pregnancy?

A: It can be used during pregnancy if prescribed by your doctor. Discuss risks and benefits with your healthcare provider.

Q: Can I drink alcohol while taking this medication?

A: Moderate alcohol may be acceptable, but it's best to consult your doctor as alcohol can affect liver function.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it's almost time for your next dose, skip the missed one. Do not double dose.