Indomethacin

Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, swelling, and inflammation in conditions like arthritis, gout, and bursitis. It works by blocking the production of prostaglandins, substances that cause pain and inflammation in the body. Indomethacin is available in various forms, including capsules, suppositories, and injections. It is a prescription medication that should be used under medical supervision.

Uses of Indomethacin

  • Treatment of osteoarthritis and rheumatoid arthritis.
  • Relief from gout attacks and acute inflammation.
  • Management of ankylosing spondylitis.
  • Reduction of pain and swelling in bursitis and tendinitis.
  • Treatment of patent ductus arteriosus in newborns.

How Indomethacin Works

Indomethacin works by inhibiting cyclooxygenase (COX) enzymes, which are responsible for producing prostaglandins. By blocking these enzymes, it reduces pain, inflammation, and fever. This makes it effective in treating conditions involving joint pain and swelling.

Benefits of Indomethacin

  • Effectively reduces pain and inflammation.
  • Provides relief in arthritis and gout.
  • Helps manage chronic inflammatory conditions.
  • Can be used in newborns for certain heart conditions.
  • Available in multiple dosage forms for easy administration.

How to Take Indomethacin

  • Take Indomethacin exactly as prescribed by your doctor.
  • Swallow the capsule whole with water.
  • Take with food or milk to reduce stomach irritation.
  • Do not exceed the recommended dosage.
  • For long-term use, regular checkups are necessary.

Types of Dosage Available

  • 25 mg Capsules
  • 50 mg Capsules
  • Suppositories
  • Intravenous Injection

Side Effects of Indomethacin

  • Nausea and vomiting.
  • Stomach pain and indigestion.
  • Dizziness and headache.
  • Increased risk of stomach ulcers.
  • Fluid retention and swelling.
  • Rarely, kidney or liver problems.

Safety Advice

  • Avoid alcohol as it may increase stomach irritation.
  • Do not use in patients with a history of ulcers or bleeding disorders.
  • Use cautiously in patients with kidney or liver disease.
  • Not recommended during pregnancy unless prescribed by a doctor.
  • Do not take with other NSAIDs to avoid side effects.

Frequently Asked Questions

Q: What is Indomethacin used for?
A: It is used to treat pain, inflammation, arthritis, gout, and bursitis.

Q: Can Indomethacin be taken daily?
A: It depends on the condition being treated. Follow your doctor’s prescription.

Q: Does Indomethacin cause stomach ulcers?
A: Long-term use can increase the risk of ulcers. Taking it with food may help.

Q: Is Indomethacin safe for kidney patients?
A: It should be used cautiously in kidney disease. Consult a doctor before use.

Q: Can Indomethacin be taken with other painkillers?
A: Avoid using it with other NSAIDs to prevent stomach and kidney issues.

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