Lamivudine + Tenofovir Disoproxil Fumarate + Efavirenz

Lamivudine + Tenofovir disoproxil fumarate + Efavirenz is a fixed-dose combination antiretroviral medication used in the treatment of HIV-1 infection. It helps lower the viral load in the blood and improves the immune system’s function, reducing the risk of HIV-related complications. This combination is often prescribed as part of highly active antiretroviral therapy (HAART) and is recommended by WHO as a first-line treatment. It is generally taken once daily under the guidance of a healthcare professional.

Uses of Lamivudine + Tenofovir + Efavirenz

• Treatment of HIV-1 infection
• Helps reduce the progression of AIDS
• Improves immunity in HIV-positive patients

How Lamivudine + Tenofovir + Efavirenz works

Lamivudine and Tenofovir are nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs), and Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI). Together, they block the action of reverse transcriptase, an enzyme HIV needs to multiply. This reduces the amount of virus in the body.

Benefits of Lamivudine + Tenofovir + Efavirenz

• Convenient once-daily fixed-dose combination
• Effectively lowers HIV viral load
• Delays progression to AIDS
• Improves patient adherence and outcomes
• Recommended in national and global HIV treatment guidelines

How to take Lamivudine + Tenofovir + Efavirenz

• Take one tablet daily on an empty stomach, usually at bedtime
• Swallow the tablet whole with water
• Take it regularly at the same time each day
• Do not skip doses, as this may reduce effectiveness

Type of Dosage Available

• Tablet

Side effects of Lamivudine + Tenofovir + Efavirenz

• Headache
• Dizziness
• Difficulty sleeping or vivid dreams
• Fatigue
• Diarrhea or nausea
• Skin rash (may be severe in rare cases)
• Changes in liver function

Safety advice

• Take medicine as prescribed; do not alter dose
• Inform your doctor of any liver or kidney disease
• Avoid alcohol and recreational drugs while on this medication
• Do not stop taking it without consulting your doctor
• Use effective contraception; not recommended during pregnancy unless advised

Frequently Asked Questions (FAQs)

Q. What is Lamivudine + Tenofovir + Efavirenz used for?
A. This combination is used to treat HIV-1 infection in adults and adolescents.

Q. Can this medicine cure HIV?
A. No, it does not cure HIV but helps control it and prevents complications.

Q. How long should I take this medicine?
A. This medicine is usually taken lifelong unless your doctor advises otherwise.

Q. Can I take it with food?
A. It is best taken on an empty stomach, usually at bedtime, to reduce side effects like dizziness.

Q. What should I do if I miss a dose?
A. Take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed one.