Lomustine

Lomustine is an anti-cancer medicine used in chemotherapy. It belongs to the group of alkylating agents that work by interfering with the growth of cancer cells. It is mainly used to treat brain tumors and Hodgkin’s lymphoma when other treatments fail. Lomustine is taken orally and works over a long duration, which allows for less frequent dosing. Due to its strong effects, it is given under strict medical supervision and requires regular monitoring.

Uses of Lomustine

• Treatment of brain tumors
• Used in managing Hodgkin’s lymphoma
• Effective in cancers resistant to other chemotherapy drugs

How Lomustine works

Lomustine works by damaging the DNA in cancer cells, preventing them from multiplying. It is a cell-cycle nonspecific drug, meaning it can attack cancer cells at any phase of their growth, making it effective for slow-growing tumors.

Benefits of Lomustine

• Helps control tumor growth
• Can be used in combination with other chemotherapy drugs
• Effective for cancers not responding to first-line treatment
• Long-lasting effect allows for monthly dosing

How to take Lomustine

Lomustine is taken as a single oral dose every 6 weeks or as directed by a doctor. It must be taken on an empty stomach, and patients should not eat for at least 2 hours before and after taking the dose. The dosage depends on body weight and overall health. Avoid repeating the dose without medical advice.

Type of Dosage Available

• Lomustine oral capsules

Side effects of Lomustine

• Nausea and vomiting
• Bone marrow suppression
• Liver toxicity
• Hair loss
• Lung damage (in rare cases)
• Loss of appetite
• Increased risk of infection

Safety Advice

• Do not take without a doctor’s prescription
• Monitor blood counts regularly
• Avoid during pregnancy or breastfeeding
• Inform your doctor about any liver or kidney problems
• Use effective contraception during treatment

Frequently Asked Questions (FAQs)

Q: What is Lomustine used for?
A: Lomustine is used to treat brain tumors and Hodgkin’s lymphoma, especially when other treatments are not effective.

Q: How often should Lomustine be taken?
A: It is usually taken once every 6 weeks as a single dose, but always follow your doctor’s instructions.

Q: Can Lomustine be taken with food?
A: No, it should be taken on an empty stomach for best absorption.

Q: What are the serious side effects of Lomustine?
A: Serious side effects include bone marrow suppression, liver problems, and lung damage.

Q: Is Lomustine safe during pregnancy?
A: No, Lomustine should not be used during pregnancy. It may harm the unborn baby.