Lorlatinib
Uses of Lorlatinib
- Treatment of ALK-positive non-small cell lung cancer
- Treatment of ROS1-positive non-small cell lung cancer
- Used in patients who have progressed on other ALK inhibitors
How Lorlatinib Works
Lorlatinib works by inhibiting the activity of abnormal ALK and ROS1 proteins, which are involved in the growth and spread of cancer cells. By blocking these proteins, Lorlatinib slows down or stops cancer progression.
Benefits of Lorlatinib
- Targets specific genetic mutations in lung cancer
- Can cross the blood-brain barrier to treat brain metastases
- Effective in patients resistant to other ALK inhibitors
- Improves progression-free survival in patients
How to Take Lorlatinib
Take Lorlatinib exactly as prescribed by your doctor, usually once daily with or without food. Swallow tablets whole and avoid missing doses. Do not stop the medication without consulting your doctor.
Type of Dosage Available
- Oral tablets
Side Effects of Lorlatinib
- Fatigue and weakness
- Swelling in arms or legs
- Changes in mood or mental function
- Elevated cholesterol and triglycerides
- Nausea, diarrhea, or constipation
- Peripheral neuropathy (tingling or numbness)
Safety Advice
- Inform your doctor about all medications you are taking
- Monitor cholesterol and liver function regularly
- Avoid driving or operating machinery if dizziness or mood changes occur
- Do not use if pregnant or breastfeeding without medical advice
- Report any severe side effects or allergic reactions immediately
Frequently Asked Questions (FAQs)
Q: Can Lorlatinib be taken with food?
A: Yes, Lorlatinib can be taken with or without food.
Q: What should I do if I miss a dose?
A: Take the missed dose as soon as you remember, but skip if it `s near the time for the next dose. Do not double dose.
Q: Does Lorlatinib cause mood changes?
A: Some patients may experience mood or mental changes; inform your doctor if this happens.
Q: Is regular blood testing necessary?
A: Yes, your doctor will monitor your blood cholesterol and liver function during treatment.
Q: Can Lorlatinib treat brain metastases?
A: Yes, Lorlatinib can cross the blood-brain barrier and is effective against brain metastases.
Medicine Not Available for Lorlatinib
Uses of Lorlatinib
- Treatment of ALK-positive non-small cell lung cancer
- Treatment of ROS1-positive non-small cell lung cancer
- Used in patients who have progressed on other ALK inhibitors
How Lorlatinib Works
Lorlatinib works by inhibiting the activity of abnormal ALK and ROS1 proteins, which are involved in the growth and spread of cancer cells. By blocking these proteins, Lorlatinib slows down or stops cancer progression.
Benefits of Lorlatinib
- Targets specific genetic mutations in lung cancer
- Can cross the blood-brain barrier to treat brain metastases
- Effective in patients resistant to other ALK inhibitors
- Improves progression-free survival in patients
How to Take Lorlatinib
Take Lorlatinib exactly as prescribed by your doctor, usually once daily with or without food. Swallow tablets whole and avoid missing doses. Do not stop the medication without consulting your doctor.
Type of Dosage Available
- Oral tablets
Side Effects of Lorlatinib
- Fatigue and weakness
- Swelling in arms or legs
- Changes in mood or mental function
- Elevated cholesterol and triglycerides
- Nausea, diarrhea, or constipation
- Peripheral neuropathy (tingling or numbness)
Safety Advice
- Inform your doctor about all medications you are taking
- Monitor cholesterol and liver function regularly
- Avoid driving or operating machinery if dizziness or mood changes occur
- Do not use if pregnant or breastfeeding without medical advice
- Report any severe side effects or allergic reactions immediately
Frequently Asked Questions (FAQs)
Q: Can Lorlatinib be taken with food?
A: Yes, Lorlatinib can be taken with or without food.
Q: What should I do if I miss a dose?
A: Take the missed dose as soon as you remember, but skip if it `s near the time for the next dose. Do not double dose.
Q: Does Lorlatinib cause mood changes?
A: Some patients may experience mood or mental changes; inform your doctor if this happens.
Q: Is regular blood testing necessary?
A: Yes, your doctor will monitor your blood cholesterol and liver function during treatment.
Q: Can Lorlatinib treat brain metastases?
A: Yes, Lorlatinib can cross the blood-brain barrier and is effective against brain metastases.
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