Mesalazine

Mesalazine, also known as 5-aminosalicylic acid (5-ASA), is a medication used to treat inflammatory bowel diseases, including ulcerative colitis and Crohn’s disease. It helps reduce inflammation in the intestines, relieving symptoms such as diarrhea, rectal bleeding, and stomach pain. Mesalazine is available in various forms, including tablets, capsules, suppositories, and enemas, and is prescribed based on the severity of the condition. Regular use helps maintain remission and prevent flare-ups.

Uses of Mesalazine

• Treatment of ulcerative colitis
• Management of Crohn’s disease
• Reduces inflammation in the digestive tract
• Prevents relapse in inflammatory bowel disease
• Relieves symptoms like diarrhea, rectal bleeding, and abdominal pain

How Mesalazine Works

Mesalazine works by reducing inflammation in the lining of the intestines. It inhibits the production of certain chemicals in the body that trigger inflammation, thereby helping to control symptoms of ulcerative colitis and Crohn’s disease. It acts locally in the intestines without significant absorption into the bloodstream, making it effective in targeting digestive tract inflammation.

Benefits of Mesalazine

• Effectively controls inflammation in the intestines
• Helps maintain remission in ulcerative colitis
• Relieves symptoms of diarrhea and rectal bleeding
• Prevents disease progression in inflammatory bowel conditions
• Available in multiple forms for targeted treatment

How to Take Mesalazine

Mesalazine should be taken as prescribed by a doctor. Oral tablets or capsules should be swallowed whole with water, without crushing or chewing. Suppositories and enemas should be used as directed for local relief. It is important to follow the prescribed dose and schedule to prevent flare-ups. Drink plenty of fluids while taking Mesalazine to stay hydrated.

Types of Dosage Available

• Mesalazine 400 mg tablets
• Mesalazine 800 mg tablets
• Mesalazine delayed-release capsules
• Mesalazine suppositories
• Mesalazine enema

Side Effects of Mesalazine

• Nausea and vomiting
• Diarrhea or constipation
• Headache and dizziness
• Abdominal pain and bloating
• Fatigue and weakness
• Skin rash and itching
• Rare but serious: Kidney issues, liver problems, and allergic reactions

Safety Advice

• Do not take if allergic to salicylates or Mesalazine
• Monitor kidney and liver function regularly
• Drink enough fluids to prevent dehydration
• Avoid use in severe kidney disease
• Consult a doctor if pregnant or breastfeeding
• Do not crush or chew extended-release tablets

Frequently Asked Questions

Q: What is Mesalazine used for?
A: Mesalazine is used to treat ulcerative colitis and Crohn’s disease by reducing inflammation in the intestines.

Q: How should I take Mesalazine tablets?
A: Swallow the tablets whole with water without crushing or chewing. Follow your doctor’s prescription.

Q: Can Mesalazine cure ulcerative colitis?
A: Mesalazine helps manage symptoms and maintain remission but does not completely cure ulcerative colitis.

Q: Are there any serious side effects of Mesalazine?
A: Serious side effects are rare but may include kidney problems, liver issues, and allergic reactions.

Q: Can I take Mesalazine if I am pregnant?
A: Consult your doctor before taking Mesalazine during pregnancy to ensure safety for you and your baby.