Methotrexate + Folic Acid

Methotrexate + Folic Acid is a combination medicine primarily used to treat autoimmune conditions like rheumatoid arthritis and certain types of cancers. Methotrexate is a disease-modifying antirheumatic drug (DMARD) that helps reduce inflammation and slows down disease progression. Folic Acid is added to prevent or reduce side effects caused by Methotrexate, such as mouth ulcers and nausea. This combination is effective in controlling symptoms and improving quality of life in long-term therapy under medical supervision.

Uses of Methotrexate + Folic Acid

• Treatment of rheumatoid arthritis
• Management of psoriasis
• Control of juvenile idiopathic arthritis
• Treatment of certain cancers like leukemia and breast cancer
• Prevention of Methotrexate-related side effects with Folic Acid

How Methotrexate + Folic Acid works

Methotrexate reduces inflammation and abnormal cell growth by blocking folic acid metabolism, while Folic Acid replenishes folate levels to reduce toxicity and support healthy cells during treatment.

Benefits of Methotrexate + Folic Acid

• Reduces joint pain and swelling in arthritis
• Slows progression of autoimmune diseases
• Helps in managing psoriasis symptoms
• Effective in treating certain types of cancer
• Minimizes Methotrexate side effects with added Folic Acid

How to take Methotrexate + Folic Acid

Take Methotrexate + Folic Acid exactly as prescribed by your doctor. Methotrexate is usually taken once a week, and Folic Acid is taken once daily or as directed. Do not increase or skip doses. Always take with food or after meals to avoid stomach upset. Regular monitoring of blood counts and liver function is necessary.

Type of Dosage Available

• Methotrexate 2.5 mg + Folic Acid 1 mg tablets
• Methotrexate injection (various strengths) with oral Folic Acid
• Weekly and daily dose packs

Side effects of Methotrexate + Folic Acid

• Nausea or vomiting
• Loss of appetite
• Mouth sores
• Dizziness or tiredness
• Hair thinning
• Liver toxicity (with long-term use)
• Low blood cell count (requires regular tests)

Safety advice

• Do not consume alcohol while on this medicine
• Avoid during pregnancy or while trying to conceive
• Regular blood tests are required
• Inform your doctor if you have liver or kidney problems
• Use effective contraception during treatment
• Do not take more than the prescribed dose

Frequently Asked Questions (FAQs)

Q. Why is Folic Acid given with Methotrexate?
A. Folic Acid helps reduce side effects of Methotrexate such as mouth ulcers, nausea, and liver issues.

Q. Can I take Methotrexate + Folic Acid daily?
A. Methotrexate is usually taken weekly, while Folic Acid is taken daily or as advised. Follow your doctor's instructions.

Q. Is Methotrexate + Folic Acid safe during pregnancy?
A. No, it is unsafe during pregnancy. Inform your doctor if you are pregnant or planning to conceive.

Q. How long does it take for this combination to work?
A. It may take a few weeks to see improvement in symptoms. Continue the treatment as prescribed for full benefits.

Q. Can I stop taking this combination if I feel better?
A. Do not stop the medicine without consulting your doctor, as stopping early can worsen your condition.