Mirabegron + Solifenacin

Mirabegron + Solifenacin is a combination medicine used for the treatment of overactive bladder (OAB). Mirabegron is a beta-3 adrenergic agonist that relaxes bladder muscles, increasing its storage capacity. Solifenacin is an anticholinergic agent that reduces bladder muscle contractions, decreasing the urgency and frequency of urination. This combination provides effective symptom control for individuals suffering from urinary incontinence, urgency, and frequent urination, improving overall bladder function and quality of life.

Uses of Mirabegron + Solifenacin – Medical Conditions Treated

• Treatment of overactive bladder (OAB)
• Reduces urinary urgency and frequency
• Prevents urinary incontinence (involuntary urine leakage)
• Improves bladder storage capacity
• Enhances control over bladder function

How Mirabegron + Solifenacin Works – Mechanism of Action

Mirabegron relaxes the bladder muscles by stimulating beta-3 adrenergic receptors, increasing bladder storage capacity. Solifenacin blocks muscarinic receptors, reducing involuntary bladder contractions. Together, they help control urination frequency and urgency, improving bladder function.

Benefits of Mirabegron + Solifenacin – Why It Is Used

• Provides effective relief from overactive bladder symptoms
• Reduces urinary frequency, urgency, and incontinence
• Improves bladder storage capacity and control
• Enhances quality of life by minimizing disruptions due to frequent urination
• Offers dual-action treatment for better symptom management

How to Take Mirabegron + Solifenacin – Dosage and Administration

This medicine is taken orally, usually once daily, with or without food. Swallow the tablet whole with water and do not crush or chew it. Follow your doctor’s prescription for the correct dosage based on your medical condition and response to treatment.

Types of Dosage Available – Forms and Strengths

• Tablets: Mirabegron 25 mg/50 mg + Solifenacin 5 mg/10 mg

Side Effects of Mirabegron + Solifenacin – Common and Severe Reactions

• Dry mouth
• Constipation
• Increased blood pressure
• Dizziness or headache
• Urinary tract infections
• Fast or irregular heartbeat (in rare cases)

Safety Advice – Precautions and Warnings

• Not recommended for individuals with severe liver or kidney disease
• Monitor blood pressure regularly, as it may cause an increase
• Use with caution in patients with a history of heart disease
• Avoid alcohol as it may worsen dizziness
• Not suitable for pregnant or breastfeeding women without medical consultation

Q. Can Mirabegron + Solifenacin cure overactive bladder permanently?
A. No, it helps manage symptoms effectively but does not cure overactive bladder permanently.

Q. How long does it take for Mirabegron + Solifenacin to show results?
A. Some patients notice improvement within a few weeks, but full benefits may take up to 8 weeks.

Q. Can I stop taking Mirabegron + Solifenacin once symptoms improve?
A. No, continue taking it as prescribed by your doctor to maintain symptom control.

Q. Does this medication cause drowsiness?
A. It may cause dizziness in some individuals, so avoid driving or operating machinery if affected.

Q. Can I take Mirabegron + Solifenacin with other bladder medications?
A. Consult your doctor before combining it with other medications to avoid potential interactions.