Nilotinib

Nilotinib is a targeted cancer medication primarily used to treat chronic myeloid leukemia (CML). It works by blocking specific proteins called tyrosine kinases that promote cancer cell growth. By inhibiting these proteins, Nilotinib helps slow down or stop the progression of leukemia. It is usually prescribed when patients are resistant or intolerant to other treatments. This oral medication requires careful dosing and regular monitoring to ensure safety and effectiveness.

Uses of Nilotinib

• Treatment of chronic myeloid leukemia (CML)
• Used for patients resistant or intolerant to other therapies

How Nilotinib works

Nilotinib blocks BCR-ABL tyrosine kinase, a protein that promotes the growth of leukemia cells, thereby slowing or stopping cancer progression.

Benefits of Nilotinib

• Effective in controlling CML
• Oral administration for patient convenience
• Helps patients resistant to other treatments
• Improves long-term survival rates

How to take Nilotinib

Take Nilotinib capsules orally as prescribed, usually twice daily on an empty stomach. Avoid eating 2 hours before and 1 hour after taking the dose. Follow your doctor’s instructions carefully.

Type of Dosage Available

• Oral capsules

Side effects of Nilotinib

• Fatigue
• Nausea and vomiting
• Headache
• Rash
• Muscle pain
• Elevated liver enzymes
• Heart rhythm changes (rare)

Safety advice

• Regular blood tests and heart monitoring are essential
• Avoid grapefruit and grapefruit juice
• Inform your doctor about other medications
• Report symptoms like chest pain or irregular heartbeat immediately
• Do not stop treatment without consulting your doctor

Frequently Asked Questions (FAQs)

Q. What is Nilotinib used for?
A. Nilotinib is used to treat chronic myeloid leukemia, especially in patients resistant to other treatments.


Q. How should I take Nilotinib?
A. Take it orally twice daily on an empty stomach, avoiding food 2 hours before and 1 hour after.


Q. What are common side effects?
A. Fatigue, nausea, headache, rash, and muscle pain are common side effects.


Q. Are there any serious risks with Nilotinib?
A. Rarely, it can cause heart rhythm problems, so regular monitoring is important.


Q. Can I stop taking Nilotinib if I feel better?
A. No, do not stop treatment without consulting your doctor.