Nirmatrelvir + Ritonavir

Nirmatrelvir + Ritonavir is an antiviral combination used to treat mild to moderate COVID-19 in people at high risk of developing severe illness. Nirmatrelvir blocks a key enzyme required by the SARS-CoV-2 virus to replicate, while Ritonavir helps boost the effectiveness of Nirmatrelvir by slowing its breakdown in the body. This combination is widely used to reduce hospitalisation and improve recovery outcomes in COVID-19 cases when administered early in the course of infection.

Uses of Nirmatrelvir + Ritonavir

• Treatment of mild to moderate COVID-19 infection
• Prevention of progression to severe disease
• Used in high-risk patients (elderly, diabetics, heart patients)

How Nirmatrelvir + Ritonavir Works

Nirmatrelvir inhibits the SARS-CoV-2 virus’s main protease, preventing the virus from multiplying. Ritonavir boosts the level of Nirmatrelvir by slowing its breakdown in the liver, making it more effective.

Benefits of Nirmatrelvir + Ritonavir

• Reduces risk of COVID-19 hospitalization
• Improves recovery time in infected individuals
• Effective when started within 5 days of symptom onset
• Oral treatment – easy to administer at home
• Suitable for high-risk patient groups

How to Take Nirmatrelvir + Ritonavir

Take the tablets orally twice a day for 5 days as directed by your doctor. It’s important to start the course as soon as possible after diagnosis and within 5 days of symptoms appearing. Do not skip doses and complete the full course even if symptoms improve.

Type of Dosage Available

• Nirmatrelvir 150 mg + Ritonavir 100 mg tablets
• Available in fixed-dose pack (daily regimen)

Side Effects of Nirmatrelvir + Ritonavir

• Altered taste (metallic or bitter taste)
• Diarrhea
• High blood pressure
• Muscle aches
• Nausea or vomiting
• Liver enzyme abnormalities (rare)

Safety Advice

• Use only under medical supervision for COVID-19
• Not for use in children under 12 years
• Inform your doctor if you have liver or kidney problems
• Check for drug interactions with other medications
• Do not share your medicine with others
• Take the full course to ensure effectiveness

Frequently Asked Questions (FAQs)

Q: What is Nirmatrelvir + Ritonavir used for?
A: It is used to treat mild to moderate COVID-19 infection in patients at risk of severe illness.

Q: When should I take this medication?
A: It should be started within 5 days of COVID-19 symptoms appearing, after a confirmed diagnosis.

Q: Can I take it without a prescription?
A: No, this medicine should only be taken with a doctor’s prescription and guidance.

Q: Are there any major side effects?
A: Some people may experience altered taste, diarrhea, or nausea. Severe effects are rare but possible.

Q: Is it safe during pregnancy or breastfeeding?
A: Consult your doctor before using this medication if you are pregnant or breastfeeding.