Obeticholic Acid

Obeticholic Acid is a prescription medication used primarily to treat primary biliary cholangitis (PBC), a chronic liver disease. It works by improving bile flow and reducing liver inflammation and fibrosis. This medicine is generally prescribed when patients do not respond adequately to ursodeoxycholic acid or in combination with it. Obeticholic Acid helps to slow disease progression and manage symptoms effectively, improving overall liver function and patient quality of life.

Uses of Obeticholic Acid

• Treatment of primary biliary cholangitis (PBC)
• Used in combination with ursodeoxycholic acid (UDCA)
• For patients who cannot tolerate UDCA

How Obeticholic Acid Works

Obeticholic Acid activates the farnesoid X receptor (FXR), which regulates bile acid production. This helps reduce bile buildup, inflammation, and fibrosis in the liver.

Benefits of Obeticholic Acid

• Improves liver function in PBC patients
• Reduces liver inflammation and scarring
• Helps manage symptoms of liver disease
• Can be used when other treatments fail

How to Take Obeticholic Acid

Obeticholic Acid should be taken as prescribed by your doctor, usually once daily. It can be taken with or without food. Dosage may vary based on liver function tests and tolerance. Do not change the dose without consulting your doctor.

Type of Dosage Available

• Tablet

Side Effects of Obeticholic Acid

• Itching (pruritus)
• Fatigue
• Abdominal pain
• Joint pain
• Nausea
• Swelling of hands or feet
• Dizziness

Safety Advice

• Not recommended during pregnancy or breastfeeding unless advised by a doctor
• Regular liver function tests are required
• Report severe itching or swelling to your doctor
• Use with caution in advanced liver disease
• Inform your doctor of any other medications you are taking

Frequently Asked Questions (FAQs)

Q. What is Obeticholic Acid used for?
A. Obeticholic Acid is used to treat primary biliary cholangitis (PBC), a chronic liver condition.

Q. Can Obeticholic Acid be taken with food?
A. Yes, it can be taken with or without food as advised by your doctor.

Q. What are the common side effects of Obeticholic Acid?
A. Itching, fatigue, abdominal pain, and nausea are common side effects.

Q. Is Obeticholic Acid safe during pregnancy?
A. It should only be used during pregnancy if clearly needed and prescribed by a doctor.

Q. How long does Obeticholic Acid take to work?
A. It may take several weeks to show improvement; regular liver tests help monitor progress.