Pegfilgrastim

Pegfilgrastim is a long-acting form of filgrastim, a medication that helps stimulate the production of white blood cells in patients undergoing chemotherapy. It is primarily used to reduce the risk of infection in cancer patients whose immune systems are weakened due to chemotherapy. Pegfilgrastim belongs to a class of drugs known as colony-stimulating factors and is typically given as a single injection per chemotherapy cycle. Its extended duration of action makes it more convenient for patients compared to daily injections of filgrastim.

Uses of Pegfilgrastim

• Prevention of neutropenia (low white blood cell count) caused by chemotherapy
• Reduction of infection risk in cancer patients
• Supportive care during bone marrow transplantation

How Pegfilgrastim Works

Pegfilgrastim works by stimulating the bone marrow to produce more neutrophils, a type of white blood cell, thereby reducing the risk of infections during chemotherapy treatment.

Benefits of Pegfilgrastim

• Reduces infection risk during chemotherapy
• Promotes faster recovery of white blood cells
• Convenient single-dose per chemotherapy cycle
• Improves treatment outcomes in cancer patients

How to Take Pegfilgrastim

Pegfilgrastim is administered as a subcutaneous injection, usually once per chemotherapy cycle. It is given at least 24 hours after chemotherapy ends. A healthcare provider may administer the injection, or it may be given at home under medical guidance.

Type of Dosage Available

• Pre-filled syringe for subcutaneous injection

Side Effects of Pegfilgrastim

• Bone pain
• Muscle aches
• Fatigue
• Headache
• Redness or swelling at the injection site
• Fever
• Rare but serious allergic reactions

Safety Advice

• Use only under medical supervision
• Inform your doctor about any allergies or prior reactions
• Monitor for signs of infection or allergic reaction
• Do not administer within 24 hours of chemotherapy
• Pregnant or breastfeeding women should consult their doctor
• Keep the medication refrigerated as instructed

Frequently Asked Questions (FAQs)

Q. What is Pegfilgrastim used for?
A. Pegfilgrastim is used to reduce the risk of infections by boosting white blood cell count in cancer patients undergoing chemotherapy.


Q. How is Pegfilgrastim administered?
A. It is given as a subcutaneous injection, usually once per chemotherapy cycle, at least 24 hours after chemotherapy ends.


Q. Can Pegfilgrastim be self-administered?
A. Yes, it can be self-administered if properly trained. However, it’s often given by a healthcare provider for safety.


Q. What are the common side effects of Pegfilgrastim?
A. Common side effects include bone pain, fatigue, muscle aches, and injection site reactions. Serious allergic reactions are rare.


Q. Is Pegfilgrastim safe during pregnancy?
A. Pegfilgrastim should only be used during pregnancy if clearly needed. Consult your doctor before use if you are pregnant or breastfeeding.