Penfluridol

Penfluridol is a long-acting antipsychotic medication used to manage chronic schizophrenia and other psychotic conditions. It belongs to the diphenylbutylpiperidine class of drugs and helps control symptoms like hallucinations, delusions, and disorganized thinking. Its long duration of action allows for weekly dosing, improving compliance in patients who have difficulty with daily medication intake. Penfluridol is effective in stabilizing mood, reducing agitation, and helping patients maintain better emotional balance over time. It should be taken only under medical supervision.

Uses of Penfluridol

  • Treatment of schizophrenia
  • Management of chronic psychotic disorders
  • Control of hallucinations and delusions
  • Long-term maintenance therapy in psychosis

How Penfluridol Works

Penfluridol works by blocking dopamine receptors in the brain, particularly D2 receptors, which helps reduce psychotic symptoms. Its long half-life provides consistent therapeutic levels for a week or more, making it effective for sustained symptom control.

Benefits of Penfluridol

  • Effective for long-term psychotic disorder management
  • Once-weekly dosing improves patient compliance
  • Reduces hallucinations, paranoia, and mood swings
  • Helps in relapse prevention
  • Improves overall quality of life

How to Take Penfluridol

Penfluridol should be taken once a week or as directed by your psychiatrist. It is usually taken orally, with or without food. Never change the dose or frequency without consulting your doctor.

Type of Dosage Available

  • Oral tablets

Side Effects of Penfluridol

  • Drowsiness or dizziness
  • Dry mouth
  • Weight gain
  • Extrapyramidal symptoms (muscle stiffness, tremors)
  • Constipation or blurred vision
  • Rarely, tardive dyskinesia or neuroleptic malignant syndrome

Safety Advice

  • Use under strict medical supervision
  • Not recommended for elderly patients with dementia-related psychosis
  • Inform your doctor of liver, heart, or kidney problems
  • Avoid alcohol and other CNS depressants
  • Do not abruptly stop the medicine without guidance

Frequently Asked Questions (FAQs)

Q. What is Penfluridol used for?
A. Penfluridol is mainly used for treating schizophrenia and chronic psychotic disorders by helping reduce hallucinations and stabilize mood.

Q. How often should I take Penfluridol?
A. It is typically taken once a week, but the exact schedule should be determined by your doctor based on your condition.

Q. Can Penfluridol cause drowsiness?
A. Yes, drowsiness is a common side effect. Avoid driving or operating heavy machinery until you know how the medicine affects you.

Q. Is Penfluridol habit-forming?
A. No, it is not habit-forming, but it should be used strictly under medical supervision to avoid side effects or misuse.

Q. Can I stop Penfluridol if I feel better?
A. No, always consult your doctor before stopping this medication. Abrupt discontinuation may lead to relapse of symptoms.

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