Polystyrene Sulfonate

Polystyrene Sulfonate is a potassium-binding resin used to treat hyperkalemia, a condition characterized by high levels of potassium in the blood. It works by exchanging potassium ions with sodium or calcium ions in the intestines, helping the body eliminate excess potassium through the stool. This medication is often used in patients with kidney problems or those undergoing dialysis, where potassium levels must be carefully controlled.

Uses of Polystyrene Sulfonate

  • Treatment of hyperkalemia (high blood potassium levels)
  • Managing potassium levels in patients with chronic kidney disease
  • Used in dialysis patients to maintain electrolyte balance

How Polystyrene Sulfonate works

Polystyrene Sulfonate binds to potassium in the intestines and replaces it with sodium or calcium, allowing excess potassium to be excreted from the body through stool.

Benefits of Polystyrene Sulfonate

  • Reduces dangerously high potassium levels
  • Helps prevent cardiac complications from hyperkalemia
  • Supports safe potassium levels in renal failure patients

How to take Polystyrene Sulfonate

Take Polystyrene Sulfonate as prescribed by your doctor, usually in powder form mixed with water or other liquid. Do not take it with orange juice or potassium-rich liquids.

Type of Dosage Available

  • Oral powder for suspension
  • Rectal enema (for hospital use)

Side effects of Polystyrene Sulfonate

  • Constipation
  • Nausea or vomiting
  • Loss of appetite
  • Hypokalemia (low potassium)
  • Electrolyte imbalance
  • Intestinal blockage (rare)

Safety advice

  • Use only under medical supervision
  • Not for use in patients with low potassium levels
  • Maintain adequate fluid intake
  • Avoid mixing with potassium-rich foods or juices
  • Inform your doctor of any gastrointestinal conditions

Frequently Asked Questions (FAQs)


Q. What is Polystyrene Sulfonate used for?
A. It is used to treat hyperkalemia by lowering high potassium levels in the blood.

Q. How does Polystyrene Sulfonate lower potassium?
A. It exchanges sodium or calcium ions with potassium in the intestines, which is then excreted in the stool.

Q. Can I take it with fruit juice?
A. No, avoid potassium-rich liquids like orange juice when taking this medication.

Q. What are the side effects of Polystyrene Sulfonate?
A. Common side effects include constipation, nausea, and in rare cases, intestinal blockage.

Q. Is it safe during pregnancy?
A. Use during pregnancy should be under the supervision of a healthcare professional.

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