Pregabalin + Nortriptyline

Pregabalin + Nortriptyline is a combination medication commonly prescribed for the management of neuropathic pain and fibromyalgia (chronic pain, fatigue & muscle tenderness). Pregabalin works by calming overactive nerve signals in the brain and spinal cord, thereby reducing pain sensations. Nortriptyline, an antidepressant, restores chemical balance in the brain, which helps regulate pain perception, mood, and sleep. Together, they provide effective relief from nerve-related pain, improve sleep quality, and enhance overall quality of life.

Uses of Pregabalin + Nortriptyline

• Relieve Neuropathic Pain - This medication helps relieve nerve pain caused by conditions such as diabetes, neuropathy, shingles, or spinal cord injury. It reduces burning, tingling, and shooting pain sensations by calming overactive nerves.
• Treat Fibromyalgia & Chronic Pain - It helps reduce widespread muscle pain, fatigue, and tenderness. This makes it useful in managing fibromyalgia and other chronic pain conditions.
• Alleviate Depression & Anxiety - Nortriptyline stabilizes mood and relieves anxiety, especially beneficial for patients suffering from chronic pain who also experience depression or anxious symptoms.
• Improve Sleep Quality - The combination helps reduce pain that disrupts sleep, thereby improving rest, sleep cycles, and overall well-being.

Available Forms & Strengths in India

Pregabalin-Nortriptyline is commonly available in:

• Dosage Form: Capsule / Tablet
• Strength: Pregabalin, Nortriptyline: (50mg, 10mg), (75 mg, 10 mg), (75 mg, 20 mg), (150 mg, 10 mg)
• (Strength may vary depending on the manufacturer.)
• How to Take: Usually taken once or twice daily, with or without food, at the same time each day, or as directed by the physician.
• Duration: Long-term treatment is needed for chronic nerve pain. Do not stop suddenly without consulting your doctor.

How Pregabalin + Nortriptyline Works

Pregabalin helps reduce the activity of overactive nerve signals, providing relief from nerve pain. Nortriptyline, a tricyclic antidepressant, enhances mood by increasing the levels of certain neurotransmitters like serotonin and norepinephrine in the brain.

Benefits of Pregabalin + Nortriptyline

• Effectively reduces nerve pain and discomfort.
• Improves sleep quality by alleviating pain and anxiety.
• Enhances overall mood and reduces symptoms of depression.
• Provides dual-action relief for pain and mental health issues.

How to Take Pregabalin + Nortriptyline

Take this medication as prescribed by your doctor, usually once or twice daily. It is recommended to take it at the same time every day to maintain consistent levels in the body. Swallow the tablet with water, and do not crush or chew it. Follow your doctor` s dosage instructions carefully.

Side Effects of Pregabalin + Nortriptyline

• Common: Dizziness, drowsiness, dry mouth, and weight gain.
• Less common: Blurred vision, constipation, and difficulty concentrating.
• Severe: Mood changes, swelling of the face or limbs, or difficulty breathing (seek immediate medical attention).

Safety Advice

• Avoid alcohol while taking this medication, as it may increase drowsiness.
• Not recommended for pregnant or breastfeeding women unless prescribed by a doctor.
• Do not operate heavy machinery or drive as this medication may cause dizziness.
• Inform your doctor if you have a history of kidney problems or heart conditions.
• Avoid abrupt discontinuation to prevent withdrawal symptoms.

Frequently Asked Questions

Q: What is Pregabalin + Nortriptyline used for?
A: It is used to treat nerve pain, fibromyalgia, and symptoms of depression and anxiety.

Q: Can I take this medication for a long time?
A: Long-term use should be monitored by your doctor to avoid dependency or side effects.

Q: What should I do if I miss a dose?
A: Take the missed dose as soon as you remember, but skip it if the next dose is near. Do not double the dose.

Q: Are there any dietary restrictions while using this medicine?
A: Generally, there are no specific restrictions, but follow your doctor` s advice regarding diet and lifestyle.

Q: Can I stop taking this medicine if I feel better?
A: No, complete the full course as prescribed by your doctor to avoid withdrawal symptoms or recurrence of symptoms.