Ribociclib

Ribociclib is a targeted therapy used in the treatment of hormone receptor-positive, HER2-negative advanced or metastatic breast cancer. It belongs to a class of medicines known as CDK4/6 inhibitors, which help slow down the growth of cancer cells. Ribociclib is usually prescribed in combination with hormone therapy such as letrozole or fulvestrant. It is an oral medication that plays a key role in extending progression-free survival in breast cancer patients. The treatment is monitored by regular blood tests to check liver function and blood counts.

Uses of Ribociclib

• Hormone receptor-positive breast cancer
• HER2-negative advanced or metastatic breast cancer
• Combination therapy with hormone treatments
• Slowing down cancer progression

How Ribociclib works

Ribociclib inhibits cyclin-dependent kinases 4 and 6 (CDK4/6), preventing cancer cells from dividing and slowing their growth.

Benefits of Ribociclib

• Effective in hormone receptor-positive breast cancer
• Delays disease progression
• Improves overall response to hormone therapy
• Oral administration for convenience
• Helps maintain quality of life in advanced cancer

How to take Ribociclib

Ribociclib is usually taken once daily for 21 consecutive days followed by a 7-day break in a 28-day cycle. Swallow the tablet whole with water at the same time each day. Follow your doctor’s instructions carefully and do not alter the dosage without medical advice. Regular monitoring is required to manage potential side effects and check treatment progress.

Type of Dosage Available

• Tablet

Side effects of Ribociclib

• Nausea and vomiting
• Fatigue
• Hair thinning
• Diarrhea or constipation
• Low white blood cell count (neutropenia)
• Liver function abnormalities
• QT prolongation (heart rhythm changes)

Safety advice

• Regular blood tests are needed to monitor liver and blood cell levels
• Inform your doctor of any heart-related issues
• Avoid grapefruit or grapefruit juice during treatment
• Use effective contraception during treatment and for at least 3 weeks after
• Not recommended during pregnancy or breastfeeding
• Report signs of infection like fever or chills promptly

Frequently Asked Questions (FAQs)

Q. What is Ribociclib used for?
A. Ribociclib is used to treat hormone receptor-positive, HER2-negative advanced breast cancer, usually with hormone therapy.

Q. How should Ribociclib be taken?
A. Take Ribociclib once daily for 21 days followed by a 7-day break, as part of a 28-day cycle.

Q. Can Ribociclib cause hair loss?
A. Hair thinning is a possible side effect, but complete hair loss is rare.

Q. Is Ribociclib safe in pregnancy?
A. No, Ribociclib should not be used during pregnancy. Use effective contraception during and after treatment.

Q. Do I need regular tests while on Ribociclib?
A. Yes, regular blood tests are required to monitor your liver function and blood cell counts.