Rifampicin + Isoniazid

Rifampicin + Isoniazid is a combination medicine used to treat tuberculosis (TB). It works by eliminating the bacteria that cause TB, helping prevent the spread of the infection. This combination is a key part of anti-tuberculosis therapy and is often used with other medications for effective treatment. Regular use, as prescribed by a doctor, ensures better recovery and lowers the risk of drug resistance. It is important to complete the full course of medication to achieve the best results and prevent reinfection.

Uses of Rifampicin + Isoniazid

• Treats active tuberculosis (TB)
• Prevents the spread of TB infection
• Used in combination with other anti-TB drugs
• Reduces the risk of drug-resistant TB
• Prevents TB in high-risk individuals

How Rifampicin + Isoniazid Works

Rifampicin and Isoniazid work together to eliminate the tuberculosis bacteria. Rifampicin inhibits the bacteria’s ability to produce proteins, preventing their growth, while Isoniazid stops the bacteria from forming a protective cell wall. This combined action effectively kills the bacteria and prevents the infection from worsening.

Benefits of Rifampicin + Isoniazid

• Effectively treats tuberculosis
• Prevents the spread of TB bacteria
• Reduces the duration of TB treatment
• Minimizes the risk of drug-resistant TB
• Helps prevent TB in exposed individuals

How to Take Rifampicin + Isoniazid

• Take the medicine exactly as prescribed by your doctor.
• Consume it on an empty stomach, preferably 1 hour before or 2 hours after a meal.
• Swallow the tablet whole with a glass of water.
• Do not skip doses, as it may lead to drug resistance.
• Complete the full course of treatment even if you feel better.

Types of Dosage Available

• Rifampicin 150mg + Isoniazid 75mg Tablets
• Rifampicin 300mg + Isoniazid 150mg Tablets

Side Effects of Rifampicin + Isoniazid

• Common side effects: Nausea, vomiting, loss of appetite
• Less common: Dark urine, yellowing of skin or eyes (jaundice)
• Severe side effects: Liver damage, allergic reactions, numbness or tingling in hands and feet
• Contact a doctor if any side effects persist or worsen

Safety Advice

• Avoid alcohol consumption, as it may increase the risk of liver damage.
• Regular liver function tests are recommended during treatment.
• Not suitable for individuals with severe liver disease.
• Pregnant and breastfeeding women should consult a doctor before use.
• Inform your doctor about other medications to avoid drug interactions.

Frequently Asked Questions

Q: How long should I take Rifampicin + Isoniazid?
A: The duration of treatment varies but usually lasts 6 months or as directed by your doctor.

Q: Can I take Rifampicin + Isoniazid with food?
A: It is best taken on an empty stomach, but if you experience stomach upset, take it with a light meal.

Q: What should I do if I miss a dose?
A: Take the missed dose as soon as you remember. If it’s close to the next dose, skip it and continue your schedule.

Q: Can I stop taking the medicine if I feel better?
A: No, stopping early may cause TB to return and become drug-resistant. Complete the full course as prescribed.

Q: Is Rifampicin + Isoniazid safe for long-term use?
A: It is safe when taken as prescribed, but regular liver function monitoring is necessary during treatment.