Rifampicin + Isoniazid

Uses of Rifampicin + Isoniazid

  • Treats active tuberculosis (TB)
  • Prevents the spread of TB infection
  • Used in combination with other anti-TB drugs
  • Reduces the risk of drug-resistant TB
  • Prevents TB in high-risk individuals

How Rifampicin + Isoniazid Works

Rifampicin and Isoniazid work together to eliminate the tuberculosis bacteria. Rifampicin inhibits the bacteria’s ability to produce proteins, preventing their growth, while Isoniazid stops the bacteria from forming a protective cell wall. This combined action effectively kills the bacteria and prevents the infection from worsening.

Benefits of Rifampicin + Isoniazid

  • Effectively treats tuberculosis
  • Prevents the spread of TB bacteria
  • Reduces the duration of TB treatment
  • Minimizes the risk of drug-resistant TB
  • Helps prevent TB in exposed individuals

How to Take Rifampicin + Isoniazid

  • Take the medicine exactly as prescribed by your doctor.
  • Consume it on an empty stomach, preferably 1 hour before or 2 hours after a meal.
  • Swallow the tablet whole with a glass of water.
  • Do not skip doses, as it may lead to drug resistance.
  • Complete the full course of treatment even if you feel better.

Types of Dosage Available

  • Rifampicin 150mg + Isoniazid 75mg Tablets
  • Rifampicin 300mg + Isoniazid 150mg Tablets

Side Effects of Rifampicin + Isoniazid

  • Common side effects: Nausea, vomiting, loss of appetite
  • Less common: Dark urine, yellowing of skin or eyes (jaundice)
  • Severe side effects: Liver damage, allergic reactions, numbness or tingling in hands and feet
  • Contact a doctor if any side effects persist or worsen

Safety Advice

  • Avoid alcohol consumption, as it may increase the risk of liver damage.
  • Regular liver function tests are recommended during treatment.
  • Not suitable for individuals with severe liver disease.
  • Pregnant and breastfeeding women should consult a doctor before use.
  • Inform your doctor about other medications to avoid drug interactions.

Frequently Asked Questions

Q: How long should I take Rifampicin + Isoniazid?
A: The duration of treatment varies but usually lasts 6 months or as directed by your doctor.

Q: Can I take Rifampicin + Isoniazid with food?
A: It is best taken on an empty stomach, but if you experience stomach upset, take it with a light meal.

Q: What should I do if I miss a dose?
A: Take the missed dose as soon as you remember. If it’s close to the next dose, skip it and continue your schedule.

Q: Can I stop taking the medicine if I feel better?
A: No, stopping early may cause TB to return and become drug-resistant. Complete the full course as prescribed.

Q: Is Rifampicin + Isoniazid safe for long-term use?
A: It is safe when taken as prescribed, but regular liver function monitoring is necessary during treatment.

Medicine Not Available for Rifampicin + Isoniazid

Uses of Rifampicin + Isoniazid

  • Treats active tuberculosis (TB)
  • Prevents the spread of TB infection
  • Used in combination with other anti-TB drugs
  • Reduces the risk of drug-resistant TB
  • Prevents TB in high-risk individuals

How Rifampicin + Isoniazid Works

Rifampicin and Isoniazid work together to eliminate the tuberculosis bacteria. Rifampicin inhibits the bacteria` s ability to produce proteins, preventing their growth, while Isoniazid stops the bacteria from forming a protective cell wall. This combined action effectively kills the bacteria and prevents the infection from worsening.

Benefits of Rifampicin + Isoniazid

  • Effectively treats tuberculosis
  • Prevents the spread of TB bacteria
  • Reduces the duration of TB treatment
  • Minimizes the risk of drug-resistant TB
  • Helps prevent TB in exposed individuals

How to Take Rifampicin + Isoniazid

  • Take the medicine exactly as prescribed by your doctor.
  • Consume it on an empty stomach, preferably 1 hour before or 2 hours after a meal.
  • Swallow the tablet whole with a glass of water.
  • Do not skip doses, as it may lead to drug resistance.
  • Complete the full course of treatment even if you feel better.

Types of Dosage Available

  • Rifampicin 150mg + Isoniazid 75mg Tablets
  • Rifampicin 300mg + Isoniazid 150mg Tablets

Side Effects of Rifampicin + Isoniazid

  • Common side effects: Nausea, vomiting, loss of appetite
  • Less common: Dark urine, yellowing of skin or eyes (jaundice)
  • Severe side effects: Liver damage, allergic reactions, numbness or tingling in hands and feet
  • Contact a doctor if any side effects persist or worsen

Safety Advice

  • Avoid alcohol consumption, as it may increase the risk of liver damage.
  • Regular liver function tests are recommended during treatment.
  • Not suitable for individuals with severe liver disease.
  • Pregnant and breastfeeding women should consult a doctor before use.
  • Inform your doctor about other medications to avoid drug interactions.

Frequently Asked Questions

Q: How long should I take Rifampicin + Isoniazid?
A: The duration of treatment varies but usually lasts 6 months or as directed by your doctor.

Q: Can I take Rifampicin + Isoniazid with food?
A: It is best taken on an empty stomach, but if you experience stomach upset, take it with a light meal.

Q: What should I do if I miss a dose?
A: Take the missed dose as soon as you remember. If it` s close to the next dose, skip it and continue your schedule.

Q: Can I stop taking the medicine if I feel better?
A: No, stopping early may cause TB to return and become drug-resistant. Complete the full course as prescribed.

Q: Is Rifampicin + Isoniazid safe for long-term use?
A: It is safe when taken as prescribed, but regular liver function monitoring is necessary during treatment.

Medicine Not Available for Rifampicin + Isoniazid

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