Riluzole

Riluzole is a prescription medication used to slow the progression of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. ALS is a neurodegenerative disorder that affects nerve cells in the brain and spinal cord, leading to loss of muscle control. Riluzole works by reducing damage to nerve cells and prolonging survival in ALS patients. It is available in tablet and oral suspension forms and is typically used under medical supervision.

Uses of Riluzole

• Slows the progression of ALS (Amyotrophic Lateral Sclerosis)
• Helps in delaying the need for ventilatory support in ALS patients
• Supports motor neuron function for a longer period

How Riluzole Works

Riluzole works by reducing the release of glutamate, a neurotransmitter that plays a role in nerve cell communication. Excess glutamate can cause nerve cell damage in ALS. By limiting glutamate activity, Riluzole helps slow down nerve degeneration, extending the patient’s ability to move and breathe independently.

Benefits of Riluzole

• Slows the progression of ALS
• Prolongs survival in ALS patients
• Delays the need for ventilatory assistance
• Reduces nerve cell damage

How to Take Riluzole

Riluzole is usually taken twice daily on an empty stomach, at least one hour before or two hours after meals. The dosage is determined by the doctor based on the patient’s condition. Swallow the tablet whole with water and follow the prescribed schedule strictly.

Types of Dosage Available

• Riluzole 50 mg tablets
• Riluzole oral suspension

Side Effects of Riluzole

• Nausea and vomiting
• Fatigue and weakness
• Dizziness
• Loss of appetite
• Elevated liver enzymes
• Breathing difficulties in rare cases

Safety Advice

• Avoid alcohol as it may worsen liver function
• Regular liver function tests are recommended
• Do not drive or operate machinery if experiencing dizziness
• Inform your doctor if you have liver disease
• Not recommended during pregnancy or breastfeeding

Frequently Asked Questions (FAQs)

Q. How does Riluzole help in ALS?
A. Riluzole helps slow down the nerve damage in ALS by reducing glutamate levels, which may prolong muscle function.

Q. Can Riluzole cure ALS?
A. No, Riluzole does not cure ALS, but it helps slow down its progression and prolongs survival.

Q. When should I take Riluzole?
A. Take Riluzole on an empty stomach, either one hour before or two hours after a meal, twice a day as prescribed.

Q. Are there any dietary restrictions while taking Riluzole?
A. Avoid alcohol and high-fat meals as they may affect how Riluzole is absorbed in the body.

Q. Does Riluzole affect liver function?
A. Yes, Riluzole may increase liver enzymes, so regular liver function tests are necessary during treatment.