Sodium Metabisulphite

Introduction

Sodium Metabisulphite is a chemical compound widely used in the pharmaceutical, food, and cosmetic industries for its antioxidant and preservative properties. It helps prevent oxidation and spoilage by releasing sulfur dioxide, which inhibits microbial growth. In medical settings, it may be used in the formulation of injections and IV fluids as a stabilizer. Sodium Metabisulphite is a powerful compound that must be used under controlled conditions due to its potential sensitivity and side effects in some individuals.

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Uses of Sodium Metabisulphite

  • Used as an antioxidant in pharmaceutical preparations
  • Preservative in injections and IV fluids
  • Prevents oxidation of active drug ingredients
  • Helps stabilize formulations containing adrenaline or catecholamines
  • Used in food and beverage processing as a preservative (non-medicinal)

How Sodium Metabisulphite works

Sodium Metabisulphite works by releasing sulfur dioxide (SO₂) when it dissolves. This gas has strong antioxidant and antimicrobial properties, which help prevent oxidation and microbial contamination in pharmaceutical products and other formulations. It stabilizes sensitive compounds and prolongs shelf life.

Benefits of Sodium Metabisulphite

  • Prevents drug degradation
  • Enhances shelf life of pharmaceutical formulations
  • Acts as an effective antioxidant
  • Maintains potency of sensitive medications
  • Useful as a preservative in IV solutions and injectables

How to take Sodium Metabisulphite

Sodium Metabisulphite is not consumed directly. It is included in formulations such as injectables or IV fluids and administered by healthcare professionals. The concentration and dosage depend on the product and the patient's medical needs. Self-administration is not recommended.

Type of Dosage Available

  • Injection formulations
  • IV fluid formulations
  • Topical and pharmaceutical excipients

Side effects of Sodium Metabisulphite

  • Allergic reactions (especially in asthmatic patients)
  • Rashes or itching
  • Breathing difficulties
  • Flushing or low blood pressure (in rare cases)
  • Throat irritation or coughing

Safety advice

  • Use only under medical supervision
  • Avoid if you have sulfite sensitivity or asthma
  • Inform your doctor about any allergic conditions
  • Not intended for direct consumption
  • Store in a cool, dry place away from light

Frequently Asked Questions (FAQs)

Q: What is Sodium Metabisulphite used for?
A: It is used as an antioxidant and preservative in pharmaceutical and food products.

Q: Is it safe for asthmatic patients?
A: No, asthmatic individuals may experience allergic reactions and should avoid it unless advised by a doctor.

Q: Can it be consumed directly?
A: No, it is not meant for direct consumption and is used as a component in formulations.

Q: What are the common side effects?
A: Allergic reactions, skin irritation, and breathing difficulties in sensitive individuals.

Q: In what forms is it available?
A: It is available as part of injectable formulations, IV fluids, and as a pharmaceutical excipient.

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