Sorafenib

Sorafenib is an oral anticancer medication used in the treatment of advanced liver cancer (hepatocellular carcinoma), kidney cancer (renal cell carcinoma), and certain types of thyroid cancer. It belongs to a class of drugs called multikinase inhibitors, which work by blocking cancer cell growth and cutting off the blood supply that tumors need to grow. Sorafenib is typically prescribed when the cancer cannot be treated with surgery or has spread to other parts of the body. It is taken by mouth under the supervision of a specialist.

Uses of Sorafenib

• Advanced hepatocellular carcinoma (liver cancer)
• Advanced renal cell carcinoma (kidney cancer)
• Locally recurrent or metastatic thyroid cancer
• Unresectable tumors

How Sorafenib works

Sorafenib blocks multiple enzymes involved in cancer cell growth and blood vessel formation, helping to slow the progression of cancer.

Benefits of Sorafenib

• Slows the growth of advanced cancers
• Improves progression-free survival in cancer patients
• Targets multiple cancer growth pathways
• Oral medication for ease of use
• May reduce tumor size in some patients

How to take Sorafenib

Take Sorafenib as prescribed by your doctor, usually twice a day on an empty stomach, at least 1 hour before or 2 hours after a meal. Swallow the tablet whole with water. Do not change the dose or stop taking it unless advised by your oncologist. Regular monitoring through blood tests and imaging may be required during the treatment period.

Type of Dosage Available

• Tablet

Side effects of Sorafenib

• Fatigue
• Diarrhea
• Loss of appetite
• Weight loss
• Skin rash or redness
• High blood pressure
• Hand-foot skin reaction
• Nausea or vomiting

Safety advice

• Do not take during pregnancy or breastfeeding
• Monitor blood pressure regularly
• Inform your doctor about liver or heart conditions
• Avoid grapefruit juice while on Sorafenib
• Regular liver function tests are recommended
• Use contraception during and after treatment as advised

Frequently Asked Questions (FAQs)

Q. What is Sorafenib used for?
A. Sorafenib is used to treat liver, kidney, and thyroid cancers that cannot be surgically removed or have spread.

Q. How should Sorafenib be taken?
A. It should be taken on an empty stomach, usually twice daily, exactly as prescribed by your doctor.

Q. Can Sorafenib cause skin problems?
A. Yes, it may cause hand-foot syndrome, rash, or skin redness. Inform your doctor if symptoms worsen.

Q. Is Sorafenib safe during pregnancy?
A. No, Sorafenib is not safe during pregnancy. Use effective contraception during treatment and consult your doctor.

Q. Can I stop taking Sorafenib if I feel better?
A. No, do not stop without your doctor's advice. The medicine must be continued as prescribed for best results.