Sunitinib

Sunitinib is an anti-cancer medicine used for treating various types of tumors and cancers, including kidney cancer and gastrointestinal stromal tumors (GIST). It belongs to a class of medicines known as tyrosine kinase inhibitors (TKIs). Sunitinib works by blocking certain proteins that signal cancer cells to grow. By doing this, it helps slow or stop the spread of cancer in the body. It is usually prescribed when other treatments are not effective or for specific advanced cancers.

Uses of Sunitinib

• Treatment of advanced kidney cancer (renal cell carcinoma)
• Gastrointestinal stromal tumors (GIST) after imatinib failure
• Pancreatic neuroendocrine tumors (pNET)
• Rare soft tissue sarcomas

How Sunitinib works

Sunitinib works by blocking specific proteins known as tyrosine kinases. These proteins help cancer cells grow and multiply. By stopping their activity, Sunitinib slows down or stops tumor growth and cuts off the blood supply to the cancer cells, helping to shrink tumors and prevent the disease from spreading.

Benefits of Sunitinib

• Slows down cancer progression
• Targets cancer cells without harming normal cells
• Improves survival in advanced cancer cases
• Reduces tumor size in kidney and pancreatic cancers
• Can be taken orally, avoiding hospital visits

How to take Sunitinib

Sunitinib should be taken exactly as prescribed by your doctor. It is usually taken once daily, with or without food. Swallow the capsule whole with a glass of water. Follow the treatment cycle and dosage duration strictly. Do not skip or double doses. Your doctor may adjust your dose based on how you respond to the treatment and your tolerance level.

Type of Dosage Available

• Capsules
• Tablets

Side effects of Sunitinib

• Nausea and vomiting
• Fatigue and weakness
• High blood pressure
• Mouth sores and diarrhea
• Skin discoloration or rash
• Changes in taste
• Low blood cell counts
• Liver function issues (in rare cases)

Safety advice

• Not recommended during pregnancy or breastfeeding
• Monitor blood pressure regularly
• Regular liver function and blood tests required
• Inform your doctor about any heart conditions
• Avoid grapefruit or grapefruit juice
• Use effective contraception during and after treatment

Frequently Asked Questions (FAQs)

Q. What is Sunitinib used for?
A. Sunitinib is used to treat kidney cancer, gastrointestinal tumors, and pancreatic neuroendocrine tumors.

Q. Can I take Sunitinib on an empty stomach?
A. Yes, Sunitinib can be taken with or without food, as advised by your doctor.

Q. Are there any foods I should avoid while taking Sunitinib?
A. Avoid grapefruit and its juice as it can interfere with how the medicine works in your body.

Q. How long should I take Sunitinib?
A. The duration of treatment depends on your response and condition. Follow your doctor's prescription strictly.

Q. Can Sunitinib cause hair loss?
A. Hair thinning or changes in hair color may occur in some people but are usually temporary.