Tegafur + Uracil

Tegafur + Uracil is a combination chemotherapy medication used to treat certain types of cancer, particularly colorectal cancer. Tegafur is a prodrug that converts into 5-fluorouracil (5-FU) in the body, which interferes with cancer cell growth. Uracil enhances the effectiveness of Tegafur by inhibiting the breakdown of 5-FU, increasing its concentration in the body. This combination allows for oral administration of chemotherapy, providing an effective treatment option. It is often used in advanced cancer cases and may be combined with other cancer therapies.

Uses of Tegafur + Uracil

• Treatment of colorectal cancer
• Treatment of other solid tumors as prescribed
• Used as adjuvant therapy post-surgery in some cancers

How Tegafur + Uracil works

Tegafur converts into 5-fluorouracil (5-FU) in the body, which disrupts DNA synthesis in cancer cells, while Uracil inhibits the breakdown of 5-FU, boosting its anti-cancer activity.

Benefits of Tegafur + Uracil

• Effective oral chemotherapy option
• Enhances anti-cancer effect with Uracil
• Convenient administration compared to intravenous chemotherapy
• Improves treatment adherence

How to take Tegafur + Uracil

Take Tegafur + Uracil capsules orally as prescribed by your doctor, usually twice daily after meals. Do not crush or chew the capsules. Follow the dosing schedule strictly and complete the full course to ensure treatment effectiveness.

Type of Dosage Available

• Oral capsules

Side effects of Tegafur + Uracil

• Nausea and vomiting
• Diarrhea
• Mouth sores
• Fatigue
• Low blood cell counts
• Skin rash
• Loss of appetite

Safety advice

• Inform your doctor if you have liver or kidney problems
• Avoid pregnancy during treatment and use effective contraception
• Report any signs of infection or unusual bleeding immediately
• Regular blood tests are required to monitor for side effects
• Avoid alcohol and other medications without consulting your doctor

Frequently Asked Questions (FAQs)

Q. What is Tegafur + Uracil used for?
A. It is used primarily to treat colorectal cancer and other solid tumors as part of chemotherapy.


Q. How do I take Tegafur + Uracil?
A. Take the capsules orally as prescribed, usually twice daily after meals. Do not crush or chew the capsules.


Q. What are common side effects?
A. Nausea, vomiting, diarrhea, mouth sores, and fatigue are common side effects.


Q. Can I become pregnant while taking Tegafur + Uracil?
A. No, it is important to avoid pregnancy during treatment and use effective contraception.


Q. Should I avoid any foods or medications while on Tegafur + Uracil?
A. Avoid alcohol and consult your doctor before taking any other medicines during treatment.