Trientine Hydrochloride

Trientine Hydrochloride is a chelating agent primarily used for the treatment of Wilson's disease—a genetic disorder that causes excess copper buildup in the body. By binding with excess copper, Trientine helps eliminate it through urine, reducing its accumulation in the liver, brain, and other organs. This medicine is typically prescribed when patients cannot tolerate penicillamine or as a long-term therapy to manage copper levels safely and effectively.

Uses of Trientine Hydrochloride

• Treatment of Wilson’s disease
• Removal of excess copper from the body
• Alternative to penicillamine for copper chelation

How Trientine Hydrochloride works

Trientine Hydrochloride binds with excess copper in the bloodstream, forming a complex that is then excreted through urine, effectively reducing copper toxicity in the body.

Benefits of Trientine Hydrochloride

• Effective copper chelation in Wilson’s disease
• Alternative option for penicillamine-intolerant patients
• Reduces symptoms like liver damage and neurological issues
• Supports long-term management of copper levels

How to take Trientine Hydrochloride

Take Trientine Hydrochloride on an empty stomach, at least 1 hour before or 2 hours after meals. Avoid taking it with iron or zinc supplements. Follow the dosage exactly as prescribed by your doctor.

Type of Dosage Available

• Capsule

Side effects of Trientine Hydrochloride

• Nausea
• Skin rash
• Abdominal pain
• Diarrhea
• Anemia
• Worsening of neurological symptoms initially

Safety advice

• Regular monitoring of copper and liver function levels is essential
• Avoid iron supplements during treatment
• Not recommended during pregnancy unless advised by a doctor
• Inform your doctor of any allergic reactions or existing health conditions
• Take on an empty stomach for best results

Frequently Asked Questions (FAQs)

Q. What is Trientine Hydrochloride used for?
A. It is used to treat Wilson’s disease by removing excess copper from the body and preventing organ damage.

Q. Can Trientine Hydrochloride be taken with food?
A. No, it should be taken on an empty stomach, at least 1 hour before or 2 hours after meals.

Q. What should I avoid while taking Trientine?
A. Avoid iron supplements and antacids, as they can reduce the effectiveness of the medicine.

Q. Is Trientine safe during pregnancy?
A. Use only if clearly needed and prescribed by a doctor, as safety in pregnancy is not well established.

Q. How long will I need to take Trientine?
A. Wilson’s disease is a lifelong condition, so Trientine may be needed long-term to manage copper levels.