Vedolizumab

Vedolizumab is a monoclonal antibody used to treat inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn’s disease in adults. It works by blocking a specific protein on white blood cells that causes inflammation in the gastrointestinal tract. Vedolizumab is typically prescribed when other treatments have not been effective. Administered as an intravenous infusion, it provides targeted relief and helps maintain remission, improving the patient’s quality of life.

Uses of Vedolizumab

• Treatment of moderate to severe ulcerative colitis
• Treatment of moderate to severe Crohn’s disease
• Helps maintain remission in inflammatory bowel diseases
• Used when other medications have failed or caused side effects

How Vedolizumab Works

Vedolizumab selectively blocks α4β7 integrin, a protein that directs white blood cells to inflamed areas in the gut. By preventing this action, it reduces inflammation and promotes healing in the digestive tract.

Benefits of Vedolizumab

• Targeted treatment for gut-specific inflammation
• Effective in inducing and maintaining remission
• Lower risk of systemic side effects
• Improves bowel health and overall quality of life
• Well-tolerated even in long-term use

How to Take Vedolizumab

Vedolizumab is given as an intravenous (IV) infusion under medical supervision. The initial doses are usually given at weeks 0, 2, and 6, followed by maintenance infusions every 8 weeks. Your doctor will determine the right schedule based on your condition and response to treatment.

Type of Dosage Available

• Intravenous infusion

Side Effects of Vedolizumab

• Headache
• Joint pain
• Nausea
• Fever
• Fatigue
• Upper respiratory tract infections
• Injection site reactions
• Rare risk of serious infections or liver problems

Safety Advice

• Administer only under medical supervision
• Inform your doctor about any infections before starting
• Do not use if you have active serious infections
• Monitor liver function and signs of allergic reactions
• Pregnant or breastfeeding women should consult a doctor
• Stay up to date with all vaccinations

Frequently Asked Questions (FAQs)

Q. What is Vedolizumab used for?
A. Vedolizumab is used to treat moderate to severe ulcerative colitis and Crohn’s disease, especially when other treatments have failed.

Q. How does Vedolizumab work?
A. Vedolizumab blocks specific white blood cells from causing inflammation in the gut, helping reduce symptoms and maintain remission.

Q. How is Vedolizumab administered?
A. It is given as an IV infusion at a clinic or hospital, starting with frequent doses and then every 8 weeks for maintenance.

Q. Can Vedolizumab cause side effects?
A. Yes, some side effects include headache, joint pain, nausea, infections, and in rare cases, liver problems or serious allergic reactions.

Q. Is Vedolizumab safe during pregnancy?
A. Pregnant or breastfeeding women should consult their doctor before using Vedolizumab to ensure it is appropriate for their condition.