Zafirlukast

Zafirlukast is a leukotriene receptor antagonist used in the prevention and long-term treatment of asthma. It works by blocking the action of certain substances (leukotrienes) that cause inflammation, tightening of airways, and increased mucus production in the lungs. Zafirlukast helps to reduce the frequency and severity of asthma attacks and is used alongside other asthma medications. It is not intended for relieving sudden breathing problems but is effective in controlling chronic asthma symptoms over time.

Uses of Zafirlukast

  • Prevention of asthma symptoms
  • Long-term management of mild to moderate asthma
  • Relief from allergic breathing conditions
  • Helps in reducing wheezing and shortness of breath

How Zafirlukast works

Zafirlukast blocks leukotriene receptors in the lungs, preventing the action of inflammatory chemicals that cause asthma symptoms like airway narrowing and mucus buildup. This helps to maintain easier breathing and reduce asthma flare-ups.

Benefits of Zafirlukast

  • Reduces asthma symptoms and prevents flare-ups
  • Improves breathing and lung function over time
  • Helpful for people with allergic asthma
  • Can be used along with inhaled corticosteroids

How to take Zafirlukast

Take Zafirlukast exactly as prescribed by your doctor, usually twice daily on an empty stomach (1 hour before or 2 hours after meals). Do not use it to treat sudden asthma attacks. Continue taking the medication regularly, even if you feel well.

Type of Dosage Available

  • Oral tablets

Side effects of Zafirlukast

  • Headache
  • Nausea or vomiting
  • Diarrhea
  • Stomach pain
  • Fever or sore throat
  • Liver enzyme changes (rare)

Safety advice

  • Do not use to treat sudden asthma attacks
  • Inform your doctor if you have liver problems
  • Regular liver function tests may be required
  • Use with caution in children below 5 years
  • Continue other asthma medications unless advised otherwise

Frequently Asked Questions (FAQs)


Q. What is Zafirlukast used for?
A. Zafirlukast is used to prevent and manage chronic asthma by reducing inflammation and airway constriction. It is not meant for treating sudden asthma attacks.

Q. Can Zafirlukast be used in children?
A. Yes, it can be used in children aged 5 years and above under medical supervision. Dosage may vary based on the child's age and condition.

Q. How long does it take for Zafirlukast to work?
A. It may take a few days to a few weeks of regular use to notice significant improvement in asthma symptoms.

Q. Can I stop taking Zafirlukast if my asthma improves?
A. No, you should continue taking it regularly unless your doctor advises you to stop. Stopping the medication may cause your symptoms to return.

Q. Is Zafirlukast safe for long-term use?
A. Yes, it is generally safe for long-term use under medical supervision, although periodic liver function monitoring is recommended.

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