Zileuton

Introduction

Zileuton is a leukotriene synthesis inhibitor used to manage and prevent symptoms of asthma. It works by reducing inflammation in the lungs, making it easier to breathe. Zileuton is typically prescribed when other asthma medications aren't effective enough. It can also help prevent asthma attacks triggered by exercise, allergens, or other environmental factors. As an oral medication, Zileuton is often used as a long-term treatment option and should be taken consistently as prescribed by a healthcare provider for best results.

Uses of Zileuton

• Prevention and treatment of chronic asthma
• Reduction of inflammation in airway disorders
• Management of exercise-induced bronchospasm
• Used as an add-on therapy in allergic respiratory conditions

How Zileuton works

Zileuton works by inhibiting the enzyme 5-lipoxygenase, which is responsible for the formation of leukotrienes. Leukotrienes are chemicals that cause inflammation, tightening of airway muscles, and increased mucus production in asthma. By blocking their production, Zileuton helps reduce airway inflammation and improve breathing.

Benefits of Zileuton

• Reduces frequency and severity of asthma attacks
• Improves breathing and lung function
• Effective when used with other asthma control medications
• Long-term control of asthma symptoms

How to take Zileuton

Zileuton should be taken exactly as prescribed by your doctor. It is usually taken orally in the form of tablets, with or without food. The dosage typically involves multiple doses per day. It’s important not to skip doses and to continue taking the medicine even if symptoms improve unless advised otherwise by your healthcare provider.

Type of Dosage Available

• Tablet (Immediate-release)
• Tablet (Extended-release)

Side effects of Zileuton

• Headache
• Upset stomach
• Dizziness
• Liver enzyme elevation
• Fatigue
• Allergic reactions (rare but serious)

Safety advice

• Regular liver function tests are recommended
• Not recommended for individuals with active liver disease
• Use with caution during pregnancy or breastfeeding
• Inform your doctor about all other medicines being taken
• Avoid alcohol to prevent liver strain

Frequently Asked Questions (FAQs)

Q: Can Zileuton be used for children?
A: Zileuton is generally prescribed for adults and adolescents above 12 years. Consult a doctor before giving it to children.

Q: Is Zileuton a steroid?
A: No, Zileuton is not a steroid. It is a leukotriene synthesis inhibitor.

Q: How long does Zileuton take to work?
A: It may take a few days to notice improvement in symptoms. Consistent use is necessary for best results.

Q: Can I stop taking Zileuton if I feel better?
A: No, do not stop the medication without consulting your doctor, even if you feel better.

Q: Is liver monitoring necessary while taking Zileuton?
A: Yes, regular liver function tests are essential to ensure safety during treatment.