Centri 800mg/160mg Tablet

Introduction

Centri 800mg/160mg Tablet is a combination medication containing Sulfamethoxazole (800mg) and Trimethoprim (160mg). This combination is used to treat a variety of bacterial infections. Sulfamethoxazole is a sulfonamide antibiotic that works by inhibiting bacterial growth, while Trimethoprim is a folic acid antagonist that prevents the growth and replication of bacteria. Together, these drugs provide a synergistic effect that effectively treats infections, particularly those caused by susceptible bacteria.

Uses of Centri 800mg/160mg Tablet

Centri 800mg/160mg Tablet is commonly prescribed for the following conditions:

• Urinary tract infections (UTIs) caused by susceptible bacteria.
• Pneumonia, particularly Pneumocystis jirovecii pneumonia (PCP) in immunocompromised patients.
• Respiratory tract infections like bronchitis.
• Traveler’s diarrhea caused by bacteria.
• Shigellosis (a bacterial infection of the intestines).
• Ear infections (otitis media) caused by susceptible organisms.

How Centri 800mg/160mg Tablet works

Centri 800mg/160mg Tablet works through the combined actions of Sulfamethoxazole and Trimethoprim. Sulfamethoxazole interferes with the synthesis of folic acid in bacteria, which is necessary for their growth and multiplication. Trimethoprim complements this action by inhibiting another enzyme involved in folic acid production. Together, they block different steps in the bacteria's ability to produce folic acid, leading to bacterial death and a reduction in infection.

Benefits of Centri 800mg/160mg Tablet

• Highly effective for treating a wide range of bacterial infections, including UTIs, pneumonia, and gastrointestinal infections.
• Combination therapy ensures a broad-spectrum effect, especially against common bacterial pathogens.
• Helps reduce symptoms such as pain, fever, and inflammation caused by bacterial infections.
• Available in an easy-to-take tablet form, improving patient compliance.

How to take Centri 800mg/160mg Tablet

Take Centri 800mg/160mg Tablet exactly as prescribed by your doctor. The typical dose for adults and children over 12 years is one tablet twice a day for a specified duration, depending on the severity and type of infection. For children under 12, the dosage will be adjusted based on weight. It is important to take the medication with a full glass of water and to continue the full course of treatment even if symptoms improve. Do not skip doses or stop treatment prematurely to ensure the infection is fully treated and to reduce the risk of resistance.

Side effects of Centri 800mg/160mg Tablet

Common side effects may include:

• Nausea or vomiting.
• Diarrhea.
• Loss of appetite.
• Rash or mild allergic reactions.
• Headache.

Severe side effects (contact your doctor immediately):

• Severe allergic reactions, including swelling of the face, lips, tongue, or throat, or difficulty breathing.
• Signs of liver damage, such as yellowing of the skin or eyes.
• Severe stomach pain or cramps.
• Blood disorders, such as unusual bruising or bleeding, or signs of infection like fever and sore throat.
• Severe skin reactions such as peeling, blistering, or redness.

Safety advice

Before taking Centri 800mg/160mg Tablet, inform your doctor if you have a history of kidney or liver disease, blood disorders, or allergies to sulfonamides or trimethoprim. This medication should be used cautiously in pregnant or breastfeeding women, and only if the potential benefits outweigh the risks. Avoid prolonged exposure to sunlight or tanning beds while taking this medication, as it can make your skin more sensitive to the sun. Drink plenty of fluids to prevent kidney problems, and do not skip doses or stop taking the medication without consulting your doctor.

Frequently Asked Questions (FAQs)

Q: Can Centri 800mg/160mg Tablet be taken with other medications?
A: Always inform your doctor about any other medications you are taking, including over-the-counter drugs and herbal supplements. Some medications may interact with Sulfamethoxazole and Trimethoprim, affecting their effectiveness or increasing the risk of side effects.

Q: Can I take Centri 800mg/160mg Tablet if I am pregnant?
A: Centri 800mg/160mg Tablet should only be used during pregnancy if the potential benefits outweigh the risks. Consult your doctor before using this medication if you are pregnant or planning to become pregnant.

Q: What should I do if I miss a dose of Centri 800mg/160mg Tablet?
A: If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once to make up for a missed one.

Q: Can Centri 800mg/160mg Tablet be used to treat viral infections?
A: No, Centri 800mg/160mg Tablet is only effective against bacterial infections. It will not work for viral infections such as the common cold or flu.