Leflunomide 20mg Tablet is a medication used to treat autoimmune diseases, specifically rheumatoid arthritis and psoriatic arthritis. It belongs to a class of drugs known as disease-modifying anti-rheumatic drugs (DMARDs). Leflunomide works by modulating the immune system to reduce inflammation, pain, and prevent further damage to the joints.

Uses of Leflunomide 20mg Tablet

Leflunomide 20mg Tablet is prescribed for the following conditions:

• Rheumatoid arthritis (RA) to reduce joint inflammation and prevent long-term damage.
• Psoriatic arthritis (PsA) to help manage inflammation and symptoms.
• Other autoimmune disorders that involve inflammation and joint damage.

How Leflunomide 20mg Tablet Works

Leflunomide 20mg Tablet works by inhibiting the enzyme dihydroorotate dehydrogenase (DHODH), which is crucial in the production of pyrimidines. Pyrimidines are necessary for the proliferation of immune cells that contribute to the inflammation process in autoimmune diseases. By inhibiting this enzyme, Leflunomide helps to suppress the overactive immune response, reducing inflammation and preventing further joint damage.

Benefits of Leflunomide 20mg Tablet

• Reduces inflammation and pain associated with rheumatoid arthritis and psoriatic arthritis.
• Prevents further joint damage and maintains joint function.
• Improves overall mobility and quality of life for individuals with autoimmune conditions.
• Helps decrease the need for stronger medications, such as steroids or biologics.
• Provides long-term disease control when used consistently as prescribed.

Dosage & Administration

• The usual starting dose of Leflunomide 20mg Tablet is 20mg once daily. Your doctor may adjust the dose depending on your response to the medication.
• Leflunomide can be taken with or without food. It is recommended to take it at the same time every day to help remember.
• If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Do not take two doses at once to make up for a missed dose.
• Always follow your healthcare provider’s instructions regarding dosage and duration of treatment.

Side Effects of Leflunomide 20mg Tablet

Common side effects of Leflunomide 20mg Tablet may include:

• Diarrhea, nausea, or abdominal discomfort
• Fatigue, dizziness, or headaches
• Skin rashes or hair thinning
• Increased liver enzyme levels (as detected in blood tests)

In rare cases, Leflunomide can cause more serious side effects, such as liver damage, severe infections, or allergic reactions. Contact your healthcare provider immediately if you experience yellowing of the skin or eyes, persistent fever, or unusual tiredness.

Safety Advice

• Leflunomide should not be used during pregnancy or breastfeeding unless specifically prescribed by your doctor.
• Regular blood tests to monitor liver function and overall health are required during treatment with Leflunomide.
• Do not stop taking Leflunomide without consulting your healthcare provider, as abrupt discontinuation may worsen your condition.
• Inform your doctor if you have a history of liver disease, kidney problems, or other serious health conditions.
• Avoid alcohol consumption during treatment, as it may increase the risk of liver damage.

Frequently Asked Questions (FAQs)

Q: How long will it take for Leflunomide 20mg Tablet to show results?

A: Leflunomide may take several weeks to show noticeable improvements in symptoms. It’s important to follow your doctor’s guidance and be patient with the treatment process.

Q: Can Leflunomide 20mg Tablet be taken with other medications?

A: Leflunomide can be taken with other medications, but it is important to inform your doctor about all medications you are using, including over-the-counter drugs and supplements, to avoid potential interactions.

Q: What should I do if I miss a dose of Leflunomide 20mg Tablet?

A: If you miss a dose, take it as soon as you remember, unless it’s almost time for your next dose. Do not take two doses at once to make up for a missed dose.

Q: Is Leflunomide 20mg Tablet safe for long-term use?

A: Leflunomide is generally safe for long-term use under the supervision of a healthcare provider. Regular monitoring of liver function and overall health is essential during treatment.