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COMPOSITION:
Tofacitinib (5mg)DESCRIPTION:
Introduction
TFCT-Nib Tablet is a medication primarily used for the treatment of cancer, particularly in cases where targeted therapy is required. It contains the active ingredient Nilotinib, a tyrosine kinase inhibitor that works by blocking specific proteins responsible for the growth of cancer cells. By inhibiting these proteins, TFCT-Nib helps to slow down or stop the progression of cancer. It is most commonly used in the treatment of chronic myelogenous leukemia (CML), a type of blood cancer. This medication is typically used under the supervision of an oncologist.
Uses of TFCT-Nib Tablet
TFCT-Nib Tablet is used for the treatment of the following conditions:
- Chronic myelogenous leukemia (CML) – an aggressive form of cancer affecting the bone marrow and blood.
- Ph+ CML – CML associated with a specific genetic mutation called the Philadelphia chromosome.
- Other cancers as determined by your healthcare provider, where targeted therapy with tyrosine kinase inhibitors is required.
How it Works
TFCT-Nib Tablet contains Nilotinib, which works by targeting and inhibiting the BCR-ABL fusion protein, a product of the Philadelphia chromosome. This protein is responsible for the uncontrolled growth of cancer cells in CML. By blocking this protein, Nilotinib stops the proliferation of cancer cells, preventing the spread of the disease and helping to manage the condition.
Benefits of TFCT-Nib Tablet
- Effective in managing chronic myelogenous leukemia (CML) and controlling the progression of the disease.
- Helps to improve survival rates and reduce the risk of relapse in patients with Ph+ CML.
- Acts as a targeted therapy, selectively attacking cancer cells and minimizing damage to normal, healthy cells.
- Can be used when other treatments have not been effective or when resistance to first-line therapies occurs.
How to Take TFCT-Nib Tablet
Follow these guidelines to take TFCT-Nib Tablet:
- Take the tablet exactly as prescribed by your doctor, typically once or twice a day.
- Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.
- It can be taken with or without food, but it's recommended to take it at the same time each day to help remember.
- If you miss a dose, take it as soon as you remember unless it's almost time for the next dose. Do not take two doses at once to make up for a missed dose.
Side Effects of TFCT-Nib Tablet
Common side effects may include:
- Fatigue, headache, or dizziness.
- Gastrointestinal symptoms such as nausea, vomiting, and diarrhea.
- Rash or other skin reactions.
- Muscle or joint pain.
Serious side effects may include:
- Severe liver problems, including jaundice (yellowing of the skin or eyes), dark urine, or abdominal pain.
- Heart problems such as irregular heartbeat or chest pain.
- Severe allergic reactions, including difficulty breathing, swelling of the face, lips, or tongue.
- Low blood counts, which can increase the risk of infection, bruising, or bleeding.
If any of these serious side effects occur, contact your healthcare provider immediately.
Safety Advice
- Inform your doctor if you have a history of heart disease, liver disease, or other serious medical conditions before starting TFCT-Nib.
- Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as TFCT-Nib may harm the baby.
- Avoid taking TFCT-Nib with certain medications, especially those that can affect your heart rhythm, such as antiarrhythmic drugs or certain antibiotics. Always check with your healthcare provider before starting new medications.
- Regular blood tests are required to monitor liver function, blood cell counts, and other health indicators during treatment.
- It is essential to stay hydrated and avoid excessive sun exposure as TFCT-Nib may increase the risk of skin reactions and dehydration.
Frequently Asked Questions
Q: Can I take TFCT-Nib Tablet if I am pregnant or breastfeeding?
A: TFCT-Nib is not recommended during pregnancy or breastfeeding. If you are pregnant or planning to become pregnant, inform your doctor before starting this medication.
Q: How long will I need to take TFCT-Nib?
A: The duration of treatment depends on your condition and response to therapy. It is typically a long-term treatment, often requiring continuous monitoring and adjustments by your doctor.
Q: Can I stop taking TFCT-Nib once my symptoms improve?
A: No, do not stop taking TFCT-Nib without consulting your doctor. Stopping treatment early can lead to relapse of the disease.
Q: What should I do if I miss a dose?
A: If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. Do not take two doses at once to make up for a missed dose.
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