Auranofin

Introduction

Auranofin is a gold-containing compound used as a disease-modifying antirheumatic drug (DMARD). It is primarily prescribed to treat rheumatoid arthritis when other treatments are ineffective or not tolerated. Auranofin works by suppressing the immune system to reduce joint inflammation, swelling, and pain. Though its use has declined due to the availability of newer DMARDs, Auranofin remains a valuable option for long-term management of autoimmune joint disorders. It is typically taken orally and monitored carefully due to potential side effects.

Uses of Auranofin

• Treatment of rheumatoid arthritis
• Reduces joint pain, stiffness, and swelling
• Slows progression of autoimmune joint damage
• May be used in research for other autoimmune diseases

How Auranofin Works

Auranofin modulates the immune system by inhibiting the activity of certain cells and enzymes responsible for inflammation. It reduces the overactive immune response in rheumatoid arthritis, helping to control symptoms and prevent further joint damage.

Benefits of Auranofin

• Helps manage chronic rheumatoid arthritis symptoms
• Slows disease progression and joint damage
• Useful when first-line treatments are ineffective
• Oral dosage is easier to administer than injectable gold therapies

How to Take Auranofin

Auranofin should be taken exactly as prescribed by your doctor, usually once or twice daily with food or milk to reduce stomach upset. Regular monitoring through blood and urine tests is required. Do not stop the medication without consulting your doctor, even if you feel better, as it may take weeks to show full benefits.

Type of Dosage Available

• Tablets

Side Effects of Auranofin

• Diarrhea (most common)
• Rashes or skin irritation
• Stomach upset or nausea
• Mouth sores
• Kidney or liver function changes (rare)
• Blood disorders like anemia or low white blood cells (rare)

Safety Advice

• Not recommended during pregnancy or breastfeeding
• Regular blood and urine tests are essential during treatment
• Avoid alcohol to reduce liver strain
• Inform your doctor about any signs of infection or unusual bleeding
• Report any skin rashes or diarrhea that becomes severe or persistent
• Keep out of reach of children

Frequently Asked Questions (FAQs)

Q: What is Auranofin used for?
A: Auranofin is mainly used to treat rheumatoid arthritis and helps reduce joint pain and inflammation.

Q: How long does Auranofin take to work?
A: It may take several weeks to notice improvement. Do not stop taking it without your doctor’s guidance.

Q: Can Auranofin cause side effects?
A: Yes, common side effects include diarrhea and rash. Serious side effects like blood changes are rare but require monitoring.

Q: Is Auranofin safe in pregnancy?
A: No, Auranofin is not recommended during pregnancy or breastfeeding. Discuss alternatives with your doctor.

Q: What should I avoid while taking Auranofin?
A: Avoid alcohol and consult your doctor before using other medications or supplements alongside Auranofin.