Chloramphenicol + Sulphacetamide

Introduction

Chloramphenicol + Sulphacetamide is a combination medication commonly used in the treatment of bacterial eye infections. Chloramphenicol is a broad-spectrum antibiotic that prevents bacteria from producing essential proteins, while Sulphacetamide is a sulfonamide antibiotic that stops bacterial growth by inhibiting folic acid synthesis. Together, they effectively treat conditions like conjunctivitis and blepharitis. This combination is available in the form of eye drops or ointment and offers fast relief from symptoms such as redness, discharge, and irritation.

Uses of Chloramphenicol + Sulphacetamide

• Bacterial conjunctivitis (pink eye)
• Blepharitis (inflammation of the eyelids)
• Keratitis (corneal inflammation)
• Post-surgical eye infections
• Prevention of secondary eye infections

How Chloramphenicol + Sulphacetamide Works

Chloramphenicol interferes with bacterial protein synthesis, preventing bacteria from multiplying. Sulphacetamide inhibits folic acid production, a vital nutrient for bacterial growth. This dual mechanism eliminates existing bacteria and stops the spread of infection in the eyes.

Benefits of Chloramphenicol + Sulphacetamide

• Broad-spectrum action against a wide range of bacteria
• Rapid relief from redness, swelling, and discharge
• Prevents progression and complications of eye infections
• Suitable for short-term bacterial infections
• Available in easy-to-use eye drop or ointment form

How to Take Chloramphenicol + Sulphacetamide

Use this medicine as prescribed by your doctor. Wash your hands before use. For eye drops, tilt your head back, pull down the lower eyelid, and place 1–2 drops into the affected eye. For ointment, apply a small amount inside the lower eyelid. Avoid touching the dropper or tube tip to prevent contamination.

Type of Dosage Available

• Eye Drops
• Eye Ointment

Side Effects of Chloramphenicol + Sulphacetamide

• Temporary stinging or burning sensation
• Blurred vision after application
• Eye redness or irritation
• Allergic reaction (swelling, itching)
• Rare: Bone marrow suppression (with prolonged use)

Safety Advice

• For ophthalmic use only; do not ingest
• Do not use in viral or fungal eye infections
• Avoid wearing contact lenses while using the medication
• Consult your doctor if you have a history of blood disorders
• Complete the prescribed course even if symptoms improve
• Use under medical supervision, especially in children

Frequently Asked Questions (FAQs)

Q: What is Chloramphenicol + Sulphacetamide used for?
A: It is used to treat bacterial infections of the eyes such as conjunctivitis, blepharitis, and keratitis.

Q: How many times a day should I apply it?
A: Usually 3–4 times daily, but follow your doctor’s instructions based on the severity of the infection.

Q: Can I use this medicine if I wear contact lenses?
A: No, remove contact lenses before application and wait at least 24 hours after treatment to resume use unless your doctor advises otherwise.

Q: Are there any serious side effects?
A: Rarely, prolonged use can lead to bone marrow suppression. Always use under medical guidance and for the prescribed duration only.

Q: Is this medicine safe for children?
A: Yes, but only under a doctor’s supervision. Pediatric doses and frequency may differ from adults.